Commentary

RNA FISH + RNA-seq = FISSEQ

rna-seq

from Biotechniques by Jeffrey M. Perkel, PhD By combining technologies, a new method reports both the expression and localization of thousands of RNA transcripts simultaneously. How will this approach change the way we see gene expression? Find out… When researchers ...

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Sequencing localized RNA in single cells by FISH

rna-seq

from greenfluorescentblog by Gal Haimovich To celebrate the 2-year anniversary of this blog, lets talk about the new Science paper in which the authors claim to performs in situ single cell, single molecule  RNA sequencing. So what’s the big deal? Well, ...

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RNA World 2.0

rna-seq

from The Scientist Most scientists believe that ribonucleic acid played a key role in the origin of life on Earth, but the versatile molecule isn’t the whole story. The ubiquity and diverse functionality of ribonucleic acid (RNA) in today’s world ...

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The Future of Next-Gen Sequencing

rna-seq

from Genetic Engineering News by Barrett Bready, M.D. & John Thompson, Ph.D. A “one-size-fits-all” sequencer doesn’t appear to be in the cards, but customizable solutions might be. With the advent of both Sanger and Maxam and Gilbert DNA sequencing technologies ...

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Focus on RNA Secondary Structure

In parallel to the genetic code for protein synthesis, a second layer of information is embedded in all RNA transcripts in the form of RNA structure. RNA structure influences practically every step in the gene expression program. However, the nature ...

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Data mine your DNA to develop better drugs

rna-seq

from wired.co.uk by by Liat Clark A team of chemists has developed a new computational drug discovery technique that targets microRNAs using genome sequencing. To demonstrate the technique, which the research team believes presents a new and efficient, general-use approach ...

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