scFAIR Consortium – a decentralized hub for single-cell RNA-Seq data standardization and unification
Single-cell RNA sequencing has generated an enormous amount of biological data over the past decade. Researchers around the world have used this technology to study everything from brain development and immune responses to cancer and rare diseases. As the ...
New eBook | RNA-seq: A peek inside the transcriptome
from Biotechniques This eBook explores advances in RNA sequencing (RNA-seq), with key content from BioTechniques’ digital hub and Taylor & Francis journals, Biotechnology and Genetic Engineering Reviews, Immunological Investigations, the Journal of Asthma and RNA Biology. In this eBook, you’ll find news, reviews and a ...
From microRNA discovery to molecular mechanisms: building robust miRNA workflows for cancer research
MicroRNAs (miRNAs) have become central to cancer research, offering powerful insights into gene regulation, disease progression and biomarker discovery. Their importance was underscored by the 2024 Nobel Prize in Physiology or Medicine, recognizing the impact of miRNA in modern ...
Total RNA Sequencing Breakthroughs Transform Research Accessibility
(From Broad Clinical Labs) RNA Research for All: How Advances in Total RNA Sequencing are Transforming Accessibility The study of the transcriptome has revolutionized our understanding of gene expression and regulation across biological systems. RNA sequencing (RNA-Seq) has emerged ...
UIC Spatial and Genome Technologies Core opens new research pathways
Speakers at the SGT Core launch event included Melissa Leone, Olga Karginova, George Chlipala, Yue Huang, Gayatry Mohapatra, Maria Sverdlov, Alvaro Hernandez, Claire White, Dan Moline, Ameen Salahudeen, Don Vander Griend. Understanding the makeup of cells and their interactions ...
Introducing Whole Transcriptome Subcellular Spatial Imaging: Reimagine Spatial Biology
Understanding the interactions between cells within their natural tissue environment is crucial for uncovering both normal physiological processes and disease mechanisms. Historically, capturing the full gene expression profile of a cell while preserving the spatial location of transcripts within ...
Droplet vs picowell – considerations for single-cell transcriptomic profiling of human colon biopsies
Advances in RNA sequencing have opened new frontiers in understanding how individual cells behave in healthy and diseased tissues. This is especially important for studying the human gastrointestinal (GI) tract, where diseases like colorectal cancer and inflammatory bowel disease ...
A systematic benchmark of Nanopore long-read RNA sequencing for transcript-level analysis in human cell lines
Understanding the full range of RNA molecules produced by our genes is crucial for insights into health and disease. While traditional short-read RNA sequencing has been instrumental, it often falls short in distinguishing between similar RNA variants, known as ...
How does UV/Vis spectroscopy enable RNA quantification?
Accurate RNA quantification is one of the most important steps in molecular biology as it influences the success of downstream applications. Optical spectroscopy is used in most laboratories to quantify and assess RNA concentration and purity quickly and non-destructively. Most ...
Advancing rare disease research innovations in RNA and long read sequencing
The Rare Disease RNA Phenotyping and Long Read Sequencing projects are advancing rare disease research by improving genetic diagnosis and data analysis. With key milestones in sequencing and collaborations with leading institutions, these technologies are enhancing our understanding of ...














Stay Connected