Identification of the post-transcriptional regulation reveals complexity in peanut pod development by Direct RNA sequencing
Researchers from the Peking University Institute of Advanced Agricultural Sciences authors explored post-transcriptional regulation, including polyadenylation, alternative splicing, and RNA adenosine methylation (m6A), in peanut pods across four developmental stages by performing direct RNA sequencing. A total of 14,627 ...
Unlocking gill health: biomarkers and management of disease in farmed Atlantic salmon
This project investigated the drivers of complex gill disease (CGD) in farmed Atlantic salmon, identified molecular biomarkers and microbial signatures of gill health, and evaluated whether functional feeds could mitigate disease progression. BACKGROUND Gill health is critical to fish ...
Tasmanian tiger RNA is first to be recovered, sequenced from an extinct animal
A new study shows the isolation and sequencing of more than a century-old RNA molecules from a Tasmanian tiger specimen preserved at room...
Cell transcriptomic atlas of the non-human primate Macaca fascicularis
Studying tissue composition and function in non-human primates (NHPs) is crucial to understand the nature of our own species. Here a team led by...
Immune cell atlas of the lymphocyte-rich classic Hodgkin lymphoma microenvironment at single-cell resolution
This study provides detailed functional and spatial characteristics of immune cells in the LR-CHL microenvironment at single-cell resolution. Researchers from British Columbia (BC) Cancer describe...
Single-cell atlas of malaria parasite gene activity provides new targets for drugs and vaccines
Researchers have mapped in fine detail the genetic changes malaria parasites go through as they prepare to infect people. The transmission stages...
Researchers use single-cell RNA sequencing to create critical new resource to boost coral reef conservation efforts
Single-cell RNA sequencing reveals 40 different cell types in Stylophora pistillata, a reef-building stony coral native to the Indo-Pacific oceans. The calcium carbonate skeleton of stony coral colonies are the...
First RNA sequencing of human retina impacts macular degeneration treatment
Assistant professor of Ophthalmology and Visual Science and of pathology Brian Hafler and his team have successfully sequenced the RNA of the human..
A mouse tissue atlas of small noncoding RNA
Small noncoding RNAs (ncRNAs) play a vital role in a broad range of biological processes both in health and disease. A comprehensive quantitative reference of small ncRNA expression would significantly advance our understanding of ncRNA roles in shaping tissue functions. ...
A single-cell landscape of high-grade serous ovarian cancer
Malignant abdominal fluid (ascites) frequently develops in women with advanced high-grade serous ovarian cancer (HGSOC) and is associated with drug resistance and a poor prognosis. To comprehensively characterize the HGSOC ascites ecosystem, a team...
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- Upcoming Conference – The Festival of Genomics & Biodata
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- Upcoming Workshop – Advanced Topics in Single Cell RNA-Seq Analysis: Multiomics ATAC-Seq & RNA-Seq
- BAP-seq – bioorthogonal masked acylating agents for proximity-dependent RNA labelling
- Single-cell RNA-seq of the rare virosphere reveals the native hosts of giant viruses in the marine environment
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