RNA-Seq Blog Transcriptome Research & Industry News
A new study shows the isolation and sequencing of more than a century-old RNA molecules from a Tasmanian tiger specimen preserved at room...
Read More »Tasmanian tiger RNA is first to be recovered, sequenced from an extinct animal
Cell transcriptomic atlas of the non-human primate Macaca fascicularis
Studying tissue composition and function in non-human primates (NHPs) is crucial to understand the nature of our own species. Here a team led by...
Read More »Immune cell atlas of the lymphocyte-rich classic Hodgkin lymphoma microenvironment at single-cell resolution
This study provides detailed functional and spatial characteristics of immune cells in the LR-CHL microenvironment at single-cell resolution. Researchers from British Columbia (BC) Cancer describe...
Read More »Single-cell atlas of malaria parasite gene activity provides new targets for drugs and vaccines
Researchers have mapped in fine detail the genetic changes malaria parasites go through as they prepare to infect people. The transmission stages...
Read More »Researchers use single-cell RNA sequencing to create critical new resource to boost coral reef conservation efforts
Single-cell RNA sequencing reveals 40 different cell types in Stylophora pistillata, a reef-building stony coral native to the Indo-Pacific oceans. The calcium carbonate skeleton of stony coral colonies are the...
Read More »First RNA sequencing of human retina impacts macular degeneration treatment
Assistant professor of Ophthalmology and Visual Science and of pathology Brian Hafler and his team have successfully sequenced the RNA of the human..
Read More »A mouse tissue atlas of small noncoding RNA
Small noncoding RNAs (ncRNAs) play a vital role in a broad range of biological processes both in health and disease. A comprehensive quantitative reference of small ncRNA expression would significantly advance our understanding of ncRNA roles in shaping tissue functions. ...
Read More »A single-cell landscape of high-grade serous ovarian cancer
Malignant abdominal fluid (ascites) frequently develops in women with advanced high-grade serous ovarian cancer (HGSOC) and is associated with drug resistance and a poor prognosis. To comprehensively characterize the HGSOC ascites ecosystem, a team...
Read More »Direct RNA sequencing and early evolution of SARS-CoV-2
Fundamental aspects of SARS-CoV-2 biology remain to be described, having the potential to provide insight to the response effort for this high-priority pathogen. University of Melbourne researchers...
Read More »The full-length transcriptome of C. elegans using direct RNA sequencing
Current transcriptome annotations have largely relied on short read lengths intrinsic to the most widely used high-throughput cDNA sequencing technologies. For example, in the annotation of the Caenorhabditis elegans transcriptome, more than half of the transcript isoforms lack full-length support and instead ...
Read More »