Technology

There are billions of neurons in the human brain, and scientists want to know how they are connected. Cold Spring Harbor Laboratory (CSHL) Professor of Neurosciences Anthony Zador, and colleagues Xiaoyin Chen and Yu-Chi Sun, published a...

Researchers at The University of Texas MD Anderson Cancer Center have developed a first-of-its-kind spatial atlas of early-stage lung cancer and surrounding normal lung tissue at single-cell resolution...

Recently structural network control methods which exploit structural controllability of complex networks have become a powerful analysis tool for identifying driver nodes (e.g., driver genes or drug targets) in...

In the brain of a person with Alzheimer’s disease, neurons degenerate and die, slowly eliminating memories and cognitive skills. However, not all neurons are impacted equally. Some types of neurons in certain brain regions are more susceptible, and even among ...

Northwestern Medicine studies are improving the understanding of epigenetic mechanisms in cancer development and progression, as well as pinpointing...

RNA sequencing (RNA-seq) is a common and widespread biological assay, and an increasing amount of data is generated with it. In practice, there are a large number of individual steps a researcher must perform before raw RNA-seq reads yield directly ...

A prerequisite to defining the transcriptome-wide functions of RNA modifications is the ability to accurately determine their location. NCI researchers have developed N4-acetylcytidine (ac4C) sequencing (ac4C-seq), a protocol for the quantitative single...

Trips-Viz is an interactive platform for the analysis and visualization of ribosome profiling (Ribo-Seq) and shotgun RNA sequencing (RNA-seq) data...

Terminal nucleotidyl transferases are enzymes that add non-templated nucleotides to RNA molecules. In the case of microRNAs, this process was shown to be functionally relevant for their maturation process...

Single-cell RNA sequencing (scRNA-seq) provides an unprecedented view of cellular diversity of biological systems. However, researchers from University of Colorado School of Medicine estimate that, across the...