Technology

University of Kentucky researchers have developed SeqOthello, an ultra-fast and memory-efficient indexing structure to support arbitrary sequence query against large collections of RNA-seq...

High-throughput expression profiling experiments with ordered conditions (e.g. time-course or spatial-course) are becoming more common for studying detailed differentiation processes or spatial patterns. Identifying dynamic changes at both the individual gene and whole transcriptome level can provide...

The ability to translate the genetic code into proteins is an essential step in all living organisms. A cornerstone of this molecular process is the ability of transfer RNA (tRNA) molecules to couple recognition...

Gene expression profiling can uncover biologic mechanisms underlying disease and is important in drug development. RNA sequencing (RNA-seq) is routinely used to assess gene expression, but costs...

Spatially resolved single-cell RNA sequencing (scRNAseq) is a powerful approach for inferring connections between a cell's identity and its position in a tissue. Researchers at the Weizmann Institute of Science recently combined scRNAseq with spatially...

MicroRNAs (miRNAs) function as master regulators of gene expression. Recent studies demonstrate that miRNA isoforms (isomiRs) play a unique role during cancer development. National Cancer Institute researchers have developed QuagmiR, the first cloud...

When different types of functional genomics data are generated on single cells from different samples of cells from the same heterogeneous population, the clustering of cells in the different samples should be coupled. Stanford University researchers formulate this “coupled clustering” ...

Genialis, which provides AI-driven, platform-enabled data integration solutions to help accelerate drug discovery, today announced a partnership with Roche to provide researchers with a complete, streamlined next-generation sequencing (NGS) workflow for gene expression profiling. By using Genialis, Roche KAPA RNA ...

1010 Genome, the California based genomics company announced the launch of data analysis services for next generation sequencing applications required by researchers and clinicians involved in research projects and studies. The Director of Research at 1010 Genome, shared more about ...

A new precision medicine platform utilizing both DNA and RNA sequencing helps identify targeted therapy options for patients with relapsed or refractory multiple myeloma. Multiple myeloma (MM) is a malignancy of plasma cells, with a median survival...