Technology

The causative agent of COVID-19 pandemic, SARS-CoV-2, has a 29,903 bases positive-sense single-stranded RNA genome. RNAs exhibit about 150 modified bases that are essential for proper function.

Lung cancer accounts for more than half of the new cancers diagnosed world-wide with poor survival rates. Despite the development of chemical, radiological, and immunotherapies, many patients do not...

In this lecture you will learn: How does scRNA-seq work and what can go wrong (empties, doublets, dropouts…) What is a UMI and why do we use them Why is scRNA-seq data challenging to analyze What are the main analysis ...

N6-methyladenosine (m6A) is the most prevalent modification of messenger RNA in mammals. To interrogate its functions and dynamics, there is a critical need to quantify m6A at three levels: site, gene and sample. Current approaches address these needs in a ...

Experts from the University of Nottingham have discovered that reversing the modification of molecular messages at synapses in the human brain, may contribute to reversible mental health...

PerkinElmer and Honeycomb Biotechnologies announced today the commercial launch of the first of its kind HIVETM scRNAseq Solution for single-cell isolation and analysis. The HIVE solution leverages a portable, handheld device for the capture, storage and RNA-Seq library preparation of a diverse range of cell types, ...

Tumor mutation burden (TMB) is a well-known efficacy predictor for checkpoint inhibitor immunotherapies. Currently, TMB assessment relies on DNA sequencing data. Gene expression profiling by RNA sequencing (RNAseq) is another type of analysis that can inform clinical decision-making and including ...

Comparisons of the molecular framework among organisms can be done on both structural and functional levels. One of the most common top-down approaches for functional comparisons is RNA...

Takara Bio USA, Inc., a wholly owned subsidiary of Takara Bio Inc., today announced the launch of the SMART-Seq® Pro kit for the ICELL8® cx Single-Cell System. This automated single-cell RNA-seq solution allows scientists to generate full-length transcriptome data from ...

The Human Tumor Atlas Network (HTAN) was created to develop high-resolution maps of many kinds of cancer so that doctors could have a more-complete view of the textured terrain of tumors — including how they change over time to become more ...