Empowering Researchers with Advanced End-to-End Analysis Tools for Single-Cell and Genetic Variation Studies [Valencia, October 3rd] — BioBam, the leading bioinformatics software company, is pleased to announce OmicsBox 3.1, its latest version packed with innovative features designed to empower researchers, ...
Read More »Establishment of a hybridoma sequencing pipeline for sequencing of antibody variable regions
The Neuroscience Monoclonal Antibody Sequencing Initiative (NeuroMabSeq) is a concerted effort to determine and make publicly available hybridoma-derived sequences of monoclonal antibodies (mAbs) valuable to neuroscience research. Over 30 years of research and development efforts including those at the UC ...
Read More »NVIGEN pioneers breakthrough in high-resolution tissue RNA sequencing with magnetic nanoparticle capture
NVIGEN, a leading provider of modern nanoparticle solutions to empower revolutionary personalized healthcare, announces its new application in RNA sequencing (RNAseq) that promises to transform our...
Read More »RNA folding studies by tRNA structure-seq inside peptide-rich droplets reveal roles of modified nucleosides at the origin of life
New research in model protocells reveals naturally occurring chemical modifications to RNA molecules help them properly fold into functional structures To investigate potential early steps taken by the first...
Read More »GiRAFR – gRNA detection and annotation in single-cell CRISPR screens
Novel methods that combine single cell RNA-seq with CRISPR screens enable high-throughput characterization of transcriptional changes caused by genetic perturbations. Dedicated software is however lacking to annotate CRISPR guide RNA (gRNA) libraries and associate them with single cell transcriptomes. Here, ...
Read More »AAV-Perturb-seq – adeno-associated virus (AAV)-mediated direct in vivo single-cell CRISPR screening
The ever-growing compendium of genetic variants associated with human pathologies demands new methods to study genotype-phenotype relationships in complex tissues in a high-throughput manner...
Read More »capTEs – Cas9-assisted profiling transposable elements expression sequencing
Transposable elements (TEs) serve as both insertional mutagens and regulatory elements in cells, and their aberrant activity is increasingly...
Read More »eSPET-seq – genome-wide probing of eukaryotic nascent RNA structure
The transcriptional intermediates of RNAs fold into secondary structures with multiple regulatory roles, yet the details of such cotranscriptional RNA...
Read More »DISCERN – deep single-cell expression reconstruction for improved cell clustering and cell subtype and state detection
Single-cell sequencing provides detailed insights into biological processes including cell differentiation and identity. While providing deep cell-specific information, the method suffers from technical constraints...
Read More »VAX-seq – mRNA vaccine quality analysis using RNA sequencing
The success of mRNA vaccines has been realised, in part, by advances in manufacturing that enabled billions of doses to be produced at sufficient quality and safety. However, mRNA vaccines must be rigorously analysed to measure their integrity and detect ...
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