Analysis Pipelines

Qlucore announces major new release for bioinformatics Version 3.8 of Qlucore Omics Explorer enables faster and improved data visualizations. Qlucore, leading software provider of powerful visualization-based bioinformatics data analysis tools, announces Qlucore Omics Explorer (QOE) version 3.8, with new features ...

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the etiological agent of coronavirus disease-2019 (COVID-19), is a novel Betacoronavirus that was first reported in Wuhan, China in Dec...

RNA molecules undergo a vast array of chemical post-transcriptional modifications (PTMs) that can affect their structure and interaction properties...

Somatic mutations and gene fusions can produce immunogenic neoantigens mediating anticancer immune responses. However, their computational prediction from sequencing data requires complex computational workflows to identify tumor-specific aberrations, derive the resulting peptides, infer patients’ Human Leukocyte Antigen (HLA) types and ...

RNA editing leads to post-transcriptional variation in protein sequences and has important biological implications. Researchers from the St. Jude Children’s Research Hospital sought to elucidate the...

Sequencing-based RNA structure probing can generate transcriptome-wide profiles of RNA secondary structures. Sufficient structural coverage is needed to obtain unbiased insights about RNA structures and functions, yet probing methods often yield uneven coverage, with missing structural scores across many transcripts. ...

Transposable elements (TEs) regulate diverse biological processes, from early development to cancer. Expression of young TEs is difficult to...

bollito is an automated, flexible and parallelizable computational pipeline for the comprehensive analysis of single-cell RNA-seq data. Starting from...

Tools for microRNA (miR) sequencing data analyses are broadly used in biomedical research. However, the complexity of computational approaches still remains a challenge for biologists with scarce experience...

Single-cell RNA sequencing (scRNA-seq) revolutionized our understanding of disease biology. The promise it presents to also transform...