In a series of studies published in Cell Press journals, STOC members used the spatially resolved transcriptomics technology Stereo-seq, developed by BGI-Research, to produce spatiotemporal cellular...
Read More »Single-cell RNA sequencing and spatial transcriptomics create first comprehensive map of human blood stem cell development
UCLA scientists and colleagues have created a first-of-its-kind roadmap that traces each step in the development of blood stem cells in the human embryo, providing scientists with a blueprint for producing...
Read More »Spatial maps of melanoma reveal how individual cells interact as cancer progresses
Melanoma is a somewhat unusual cancer—one that blooms before our very eyes, often on sun-exposed skin, and can quickly become deadly as it turns our...
Read More »Cell transcriptomic atlas of the non-human primate Macaca fascicularis
Studying tissue composition and function in non-human primates (NHPs) is crucial to understand the nature of our own species. Here a team led by...
Read More »The complete sequence of a human genome
Since its initial release in 2000, the human reference genome has covered only the euchromatic fraction of the genome, leaving important heterochromatic regions unfinished. Addressing the remaining 8%...
Read More »Human Lung Cell Atlas launched!
Human Lung Cell Atlas launched! On 11 March 2022 the discovAIR consortium officially launched the Human Lung Cell Atlas (HLCA) during the ERS Lung Science Conference in Estoril, Portugal. Malte Lücken (Helmholtz Center Munich) introduced the HLCA during his presentation ...
Read More »VINE-seq – a method for isolating and analysing the elusive cells of the blood–brain barrier
The human brain vasculature is of great medical importance: its dysfunction causes disability and death, and the specialized structure it forms...
Read More »A single-cell resolution atlas of human adenomas and serrated polyps sets framework for precision surveillance of colorectal cancer
A team of Vanderbilt researchers has revealed some of the mechanisms by which polyps develop into colorectal cancer, setting the framework for improved surveillance for the cancer utilizing precision...
Read More »CellDepot – A Unified Repository for scRNA-seq Data and Visual Exploration
CellDepot containing over 270 datasets from 8 species and many tissues serves as an integrated web application to empower scientists in exploring single-cell RNA-seq (scRNA-seq) datasets and comparing the datasets among various studies through a user-friendly interface with advanced visualization ...
Read More »Short-read and long-read RNA sequencing of mouse hematopoietic stem cells at bulk and single-cell levels
Hematopoietic stem cells (HSCs) lie at the top of the differentiation hierarchy. Although HSC and their immediate downstream, multipotent progenitors (MPP) have full multilineage differentiation capacity, only...
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