The world is sitting on a wealth of knowledge that has yet to be fully realized. Researchers around the globe generate huge amounts of biomedical data across an enormous spectrum of specialties – clinical data, genomic data, epidemiological data – ...
Read More »The ENCODE4 long-read RNA-seq collection reveals distinct classes of transcript structure diversity
The majority of mammalian genes encode multiple transcript isoforms that result from differential promoter use, changes in exonic splicing, and alternative 3’ end choice. Detecting and quantifying transcript isoforms across tissues, cell types, and...
Read More »Single-cell atlas of the human kidney provides new resources to study kidney disease
What causes certain individuals who experience a sudden decline in kidney function to develop kidney disease while others recover? A new study co-led...
Read More »HuBMAP – what healthy human tissue looks like
Stanford Medicine scientists describe details of the human intestine and placental tissue as part of the National Institute of Health’s Human Biomolecular Atlas Program More often than not, studies of human biology are conducted when the body is under duress ...
Read More »Scientists map single-cell spatial distribution atlas of macaque cortex
A team of nearly 100 scientists recently mapped the cell-type taxonomy in the macaque cortex and revealed the relationship between cell-type composition and various primate brain regions by using the self-developed spatial transcriptome...
Read More »A cellular and molecular spatial atlas of dystrophic muscle
Asynchronous skeletal muscle degeneration/regeneration is a hallmark feature of Duchenne muscular dystrophy (DMD); however, traditional -omics technologies that lack spatial...
Read More »Largest cell map of human lung reveals insights into disease
By combining data from nearly 40 studies, researchers created the first integrated single-cell atlas of the lung, revealing rare cell types and highlighting cellular differences between healthy...
Read More »The Curated Cancer Cell Atlas – a comprehensive pan-cancer single-cell RNA-sequencing dataset
Each tumour contains diverse cellular states that underlie intratumour heterogeneity (ITH), a central challenge of cancer therapeutics. Dozens of recent...
Read More »New pan-cancer single-cell T cell atlas reveals new details of tumor microenvironment
A new study led by researchers at The University of Texas MD Anderson Cancer Center, published today in Nature Medicine, provides a deeper...
Read More »New RNA sequencing method reveals bacterial reaction to antibiotics in five minutes
Researchers at Karolinska Institutet have developed a molecular method able to detect whether or not bacteria respond to antibiotics within minutes...
Read More »