Single-cell RNA sequencing (scRNA-seq) is developing rapidly, and investigators seeking to use this technology are left with a variety of options...
Read More »A large-scale binding and functional map of human RNA-binding proteins
Many proteins regulate the expression of genes by binding to specific regions encoded in the genome. Here researchers from the University of California San Diego introduce a new data set of RNA elements in the human genome that are recognized by RNA...
Read More »A comprehensive description of the human tissue virome in healthy individuals
"Hidden" associations between the human virome and human health and diseaseHuman-resident microbes can influence both health and disease. Investigating the microbiome using next-generation sequencing(*1) technology has revealed examples...
Read More »Uniform analysis of coronavirus and SARS-COV-2 nanopore direct RNA sequencing datasets
Researchers from the Centre for Genomic Regulation (CRG) have launched a new database to advance the international research efforts studying COVID-19. The publicly-available, free-to-use resource (https://covid.crg.eu) can be used by researchers from around the world to study how different variations of the ...
Read More »Construction of a human cell landscape at single-cell level
Single-cell analysis is a valuable tool to dissect cellular heterogeneity in complex systems. Yet, a comprehensive single-cell atlas has not been achieved for humans. A team led by researchers at Zhejiang University School of Medicine used single-cell mRNA sequencing ...
Read More »Single cell RNA-Seq reveals the full life cycle of unicellular organisms
Plasmodium parasites, the causative agent of malaria, are single-celled organisms with distinct morphological developmental stages each specialized to inhabit vastly different environments...
Read More »Atlas of RNA sequencing profiles for normal human tissues
Comprehensive analysis of molecular pathology requires a collection of reference samples representing normal tissues from healthy donors. For the available limited collections of normal...
Read More »Allen Institute beta releases new RNA-Seq data analysis tool
The Allen Institute for Brain Science today announced the beta release of two new data analysis tools. One, called RNA-Seq Data Navigator, allows researchers to visualize categories of brain cells based on their gene similarity patterns. These open data analysis ...
Read More »MetaMap – An atlas of metatranscriptomic reads in human disease-related RNA-seq data
With the advent of the age of big data in bioinformatics, large volumes of data and high performance computing power enable researchers to perform re-analyses of publicly available datasets...
Read More »An anatomic transcriptional atlas of human glioblastoma
Glioblastoma is an aggressive brain tumor that carries a poor prognosis. The tumor’s molecular and cellular landscapes are complex, and their relationships to histologic features routinely used...
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