Data Sets

New Cancer Genomics Datasets -TCGA and More

rna-seq

Omicsoft Corporation, a leader in cancer genomics solutions, announces its latest Q2 OncoLand release, containing new TCGA data and ICGC data, and exciting features for search and analytics. Cary, NC (PRWEB)July 21, 2015 Omicsoft Corporation, an industry leader in cancer ...

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Calling genotypes from public RNA-sequencing data enables identification of genetic variants that affect gene-expression levels

RNA-sequencing (RNA-seq) is a powerful technique for the identification of genetic variants that affect gene-expression levels, either through expression quantitative trait locus (eQTL) mapping or through allele-specific expression (ASE) analysis. Given increasing numbers of RNA-seq samples in the public domain, ...

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Genome-wide map of regulatory interactions in the human genome

rna-seq

Increasing evidence suggests that interactions between regulatory genomic elements play an important role in regulating gene expression. Researchers at Stanford University School of Medicine generated a genome-wide interaction map of regulatory elements in human cells (ENCODE tier 1 cells, K562, ...

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Study finds RNA-Seq, like microarrays, only accurate for relative expression, not absolute quantitation

rna-seq

The collborators at the SEQC/MAQC-III Consortium present primary results from the Sequencing Quality Control (SEQC) project, coordinated by the US Food and Drug Administration. Examining Illumina HiSeq, Life Technologies SOLiD and Roche 454 platforms at multiple laboratory sites using reference ...

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The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundance

rna-seq

The concordance of RNA-sequencing (RNA-seq) with microarrays for genome-wide analysis of differential gene expression has not been rigorously assessed using a range of chemical treatment conditions. Here a team led by researchers atuse at the US FDA comprehensive study design ...

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Multi-platform assessment of transcriptome profiling using RNA-seq in the ABRF next-generation sequencing study

rna-seq

High-throughput RNA sequencing (RNA-seq) greatly expands the potential for genomics discoveries, but the wide variety of platforms, protocols and performance capabilitites has created the need for comprehensive reference data. Here the authors describe the Association of Biomolecular Resource Facilities next-generation ...

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