An open single-cell RNA-seq atlas reveals neural differentiation dynamics in sea urchin development
RNA sequencing at single-cell resolution reveals developmental cell states in sea urchin embryos, helping researchers trace neurogenesis and explore gene expression...
First cell type-specific gene regulatory maps for Alzheimer’s disease
Newly developed data analysis method uncovers causal mechanisms of disease Public health researchers use newly developed data analysis method to build the first cell type-specific gene regulatory maps for Alzheimer’s disease, revealing the genetic mechanisms operating within patients’ brains. The ...
Mount Sinai researchers help create largest immune cell atlas of bone marrow in multiple myeloma patients
Scientists at the Icahn School of Medicine at Mount Sinai, in partnership with the Multiple Myeloma Research Foundation (MMRF) and in collaboration with leading institutions across the country, have helped generate the largest single-cell immune cell atlas of the bone marrow in patients ...
Mapping 10 million immune cells to decode disease mechanisms, new atlas and AI model pave way for precision immunotherapy
On January 8, 2026, a multi-institutional research team led by the State Key Laboratory of Genome and Multi-omics Technologies (initiated by BGI-Research), working with clinical and academic partners including Ruijin Hospital affiliated with Shanghai Jiao Tong University School of ...
Temporal and spatial atlas of eosinophil specialization across tissues
Eosinophils are a type of white blood cell most people have heard of in the context of allergies or parasitic infections. But these cells actually play many roles in the body including helping control immune responses, supporting metabolism and ...
Unraveling hair aging – a molecular atlas of human hair follicle senescence drawn by single-cell and spatiotemporal sequencing
Hair loss and graying, the earliest visible signs of skin aging, are fundamentally driven by the functional decline of the hair follicle stem cells (HFSCs) and their surrounding niche. The research, led by researchers at BGI Shenzhen, leveraging single-cell ...
Detailed cell map unlocks secrets of how reproductive organs form
Scientists chart a comprehensive cell atlas of the developing human reproductive system, offering new clues into congenital disorders New research has mapped the cell types that specialise to form reproductive organs in both sexes, identifying key genes and signals ...
Human gene maps are biased towards European ancestries
A study published today in Nature Communications by researchers from CRG and BSC-CNS shows that human gene maps lack global representation because they were built mainly using data from individuals of European ancestry. Human gene maps contain major blind ...
GREGoR – accelerating genomics for rare diseases
Researchers from a group of universities are advancing our understanding of rare diseases through the Genomics Research to Elucidate the Genetics of Rare Diseases (GREGoR) Consortium. While individual rare diseases may each affect only a small number of people, ...
So3D – a comprehensive three-dimensional spatial omics resource for decoding tissue architecture in physiology and disease
Researchers from Harbin Medical University have developed a powerful new resource called So3D that helps scientists explore how cells are organized and interact within three-dimensional tissues. Traditional biological studies often rely on two-dimensional data, which can overlook the complex ...
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- Upcoming Conference – The Festival of Genomics & Biodata
- Gene trajectory inference for single-cell data by optimal transport metrics
- Upcoming Workshop – Advanced Topics in Single Cell RNA-Seq Analysis: Multiomics ATAC-Seq & RNA-Seq
- BAP-seq – bioorthogonal masked acylating agents for proximity-dependent RNA labelling
- Single-cell RNA-seq of the rare virosphere reveals the native hosts of giant viruses in the marine environment
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