Bonsai reconstructs tree representations for distortion-free visualization and exploration of high-dimensional data
Modern biology research can now generate valuable data on an unprecedented scale. But there is one major obstacle: making sense of these complex high-dimensional datasets. A team at the University of Basel, Switzerland, has developed a new tool that ...
MiRQuery – a user-friendly web app for the interactive analysis and visualization of microRNA sequencing data
MicroRNAs, or miRNAs, are small RNA molecules that help control how genes are expressed. Rather than coding for proteins themselves, miRNAs can bind to messenger RNAs, or mRNAs, and reduce the amount of protein those messages produce. Because a ...
CellWhisperer – multimodal learning enables chat-based exploration of single-cell data
Researchers from the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences have introduced a powerful new tool called CellWhisperer that changes how scientists can explore complex single-cell data. Single-cell sequencing has transformed the life sciences by ...
LnCeVar 2.0 – an updated resource and web tools for genomic variations disrupting ceRNA networks
Researchers Harbin Medical University have released LnCeVar 2.0, a powerful database designed to help scientists explore how small genetic variations affect cellular communication in diseases such as cancer. The update integrates RNA sequencing and single-cell transcriptomics data to reveal ...
Uncalled4 – a toolkit for nanopore signal alignment, analysis and visualization
Nanopore sequencing has revolutionized the way scientists analyze DNA and RNA, allowing them to detect genetic sequences and modifications without extra processing steps. However, accurately identifying certain nucleotide modifications—especially in RNA—remains a challenge. A research team from Johns Hopkins ...
paraCell – interactive analysis and visualization of standard and dual host-parasite single-cell RNA-seq data
Researchers from the University of Glasgow have developed paraCell, a new software tool designed to make single-cell RNA sequencing (scRNA-seq) data more accessible to parasitologists. While single-cell transcriptomic datasets have expanded dramatically, analyzing them often requires advanced computational skills, ...
tagtango – an application to compare single-cell annotations
Single-cell analysis has become an essential method for studying the individual cells that make up tissues and organs. Unlike traditional methods, which analyze groups of cells, single-cell technologies allow researchers to examine the unique characteristics of each cell. This ...
tomoseqr – spatial reconstruction and visualization of 3D gene expression patterns based on RNA tomography
RNA tomography is an innovative technique used to map gene expression patterns in three dimensions (3D). Imagine trying to get a detailed picture of how genes are active within the cells of a tissue sample, not just from a ...
scHetG – Structure-preserved integration of scRNA-seq data using heterogeneous graph neural network
Single-cell RNA sequencing (scRNA-seq) is a powerful technique that allows scientists to study individual cells and their gene activity. This method has revolutionized our understanding of cell states and how different cells behave in various environments. However, when researchers ...
Visualizing scRNA-Seq data at population scale with GloScope
Single-cell RNA sequencing (scRNA-seq) has revolutionized biology by allowing scientists to study gene activity in individual cells. However, as researchers look at more complex biological questions, they often need to compare data across many samples, such as cells from ...
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- Single-cell RNA-seq of the rare virosphere reveals the native hosts of giant viruses in the marine environment
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