RNA-sequencing has become one of the most used high-throughput approaches to gain knowledge about the expression of all different RNA subpopulations. However, technical artifacts, either introduced during library preparation and/or data analysis, can influence the detected RNA expression levels. A ...
Read More »Researchers combine RNA-Seq datasets and apply Uniform Manifold Approximation and Projection (UMAP) to create new brain atlas
Sometimes, in the quest for new data, scientists forget that existing datasets can be treasure troves for new discoveries. One such undermined scientific...
Read More »Structure-preserving visualization for single-cell RNA-Seq profiles using deep manifold transformation with batch-correction
Dimensionality reduction and visualization play an important role in biological data analysis, such as data interpretation of single-cell RNA sequences (scRNA...
Read More »DeepBIO – automated and interpretable deep-learning platform for high-throughput biological sequence functional analysis.
Shandong University researchers have developed DeepBIO, the first-of-its-kind automated and interpretable deep-learning platform for high-throughput biological sequence functional analysis. DeepBIO is a one-stop-shop web service that enables...
Read More »CF-Seq – rapid re-analysis of cystic fibrosis pathogen RNA sequencing studies
Researchers studying cystic fibrosis (CF) pathogens have produced numerous RNA-seq datasets which are available in the gene expression omnibus (GEO).
Read More »GEOexplorer – a webserver for gene expression analysis and visualisation
Gene Expression Omnibus (GEO) is a database repository hosting a substantial proportion of publicly available high throughput gene expression data. Gene expression analysis is a powerful tool to gain insight into the mechanisms and processes...
Read More »The complete sequence of a human genome
Since its initial release in 2000, the human reference genome has covered only the euchromatic fraction of the genome, leaving important heterochromatic regions unfinished. Addressing the remaining 8%...
Read More »SeqCVIBE – interactive analysis, exploration, and visualization of RNA-Seq data
The rise of modern gene expression profiling techniques, such as RNA-Seq, has generated a wealth of high-quality datasets spanning all fields...
Read More »CellDepot – A Unified Repository for scRNA-seq Data and Visual Exploration
CellDepot containing over 270 datasets from 8 species and many tissues serves as an integrated web application to empower scientists in exploring single-cell RNA-seq (scRNA-seq) datasets and comparing the datasets among various studies through a user-friendly interface with advanced visualization ...
Read More »Dashboard-style interactive plots for RNA-seq analysis are R Markdown ready with Glimma 2.0
Glimma 1.0 introduced intuitive, point-and-click interactive graphics for differential gene expression analysis. Researchers at the Walter and Eliza Hall Institute of Medical Research present a major update to Glimma that brings improved interactivity and...
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