Researchers at Vanderbilt University Medical Center have published the largest single-site adipose tissue atlas known to date. A tissue atlas is a...
Read More »Single-cell Mayo Map (scMayoMap) – an easy-to-use tool for cell type annotation in single-cell RNA-sequencing data analysis
Single-cell RNA-sequencing (scRNA-seq) has become a widely used tool for both basic and translational biomedical research. In scRNA-seq data analysis, cell type annotation is an essential but challenging step...
Read More »How to build a cellular map of the musculoskeletal system
A single-cell resolution atlas of the human musculoskeletal system could be transformative to understanding and treating conditions including arthritis, cancer and fractures. To generate a single...
Read More »Single-nuclei characterization of pervasive transcriptional signatures across organs in response to COVID-19
Infection by coronavirus SARS-CoV2 is a severe and often deadly disease that has implications for the respiratory system and multiple organs across the human body. While the effects in the lung have...
Read More »The Human Breast Cell Atlas – world’s most comprehensive single-cell atlas of healthy breast tissue
The Human Breast Cell Atlas, recently published in Nature, is a landmark achievement for mammary biology as the world’s most comprehensive atlas of healthy breast tissue. The current “atlas era” of cell biology represents a marked shift in the field. Whereas ...
Read More »Strand-specific RNA sequencing unveils wheat’s long non-coding RNAs : A leap in understanding grain development
Wheat is a global staple food and plays a pivotal role in the livelihoods of billions of people. Although long non-coding RNAs (lncRNAs) have been recognized as crucial regulators of numerous biological processes...
Read More »HuBMAP – what healthy human tissue looks like
Stanford Medicine scientists describe details of the human intestine and placental tissue as part of the National Institute of Health’s Human Biomolecular Atlas Program More often than not, studies of human biology are conducted when the body is under duress ...
Read More »Scientists map single-cell spatial distribution atlas of macaque cortex
A team of nearly 100 scientists recently mapped the cell-type taxonomy in the macaque cortex and revealed the relationship between cell-type composition and various primate brain regions by using the self-developed spatial transcriptome...
Read More »BarleyExpDB – an integrative gene expression database for barley
RNA-sequencing (RNA-seq) has been widely used to study the dynamic expression patterns of transcribed genes, which can lead to new biological insights. However, processing and analyzing these huge...
Read More »BEETLE ATLAS – a definitive, tissue-specific transcriptomic resource based on RNA-Seq data for the Tribolium community
More than half of all extant metazoan species on earth are insects. The evolutionary success of insects is linked with their ability to osmoregulate, suggesting that they have evolved unique physiological mechanisms to maintain water balance. In beetles (Coleoptera)—the largest ...
Read More »