The GENCODE CLS project – massively expanding the lncRNA catalog through capture long-read RNA sequencing
Understanding how genomes work depends on knowing where genes are and what they produce. While protein-coding genes are relatively well annotated, long non-coding RNAs, or lncRNAs, have remained one of the least understood parts of the genome. These RNAs ...
PERlncDB – new platform developed to explore epigenetic regulation of plant long non-coding RNAs
Long non-coding RNAs (lncRNAs) are RNA transcripts longer than 200 nucleotides that do not code for proteins. Once considered mere transcriptional noise, lncRNAs are now known to play vital roles in plant growth, development, and responses to environmental stress. However, ...
A DNA search engine
Computer scientists at ETH Zurich have developed a digital tool capable of searching through millions of published DNA records in a matter of seconds. This can significantly accelerate research into antibiotic resistance and unknown pathogens. DNA datasets can be ...
GREGoR – accelerating genomics for rare diseases
Researchers from a group of universities are advancing our understanding of rare diseases through the Genomics Research to Elucidate the Genetics of Rare Diseases (GREGoR) Consortium. While individual rare diseases may each affect only a small number of people, ...
LnCeVar 2.0 – an updated resource and web tools for genomic variations disrupting ceRNA networks
Researchers Harbin Medical University have released LnCeVar 2.0, a powerful database designed to help scientists explore how small genetic variations affect cellular communication in diseases such as cancer. The update integrates RNA sequencing and single-cell transcriptomics data to reveal ...
PCsRNAdb: a comprehensive resource of small noncoding RNAs across cancers
Researchers from Sun Yat-sen University have developed an extensive new database that could deepen our understanding of small noncoding RNAs, or sncRNAs, in cancer. These tiny RNA molecules, which include miRNAs, piRNAs, and tRNA- and rRNA-derived fragments, play important ...
MetaGraph – efficient and accurate search in petabase-scale sequence repositories
The amount of biological sequencing data available in public databases is growing at an astonishing rate. Researchers now have access to millions of DNA and RNA sequences collected from across all forms of life, including viruses, bacteria, plants, animals, ...
MOADE – a multimodal autoencoder for dissociating bulk multi-omics data
Understanding complex tissues and tumors is a major challenge in biology, especially when different types of cells are mixed together in bulk samples. Traditional methods often rely only on RNA sequencing data to separate these cell types, which can ...
The Biodiversity Cell Atlas – mapping the tree of life at cellular resolution
Cells are the building blocks of life, but scientists still know surprisingly little about how diverse cell types are across the many branches of the tree of life. Advances in single-cell technologies and genome sequencing are opening the door ...
Scientists debut a new foundational atlas of the plant life cycle
Salk Institute researchers map every cell type and developmental state across the entire life cycle of model plant Arabidopsis Nearly everything you know about plants was first discovered in a plant you’ve likely never heard of. Arabidopsis thaliana, also known ...
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Most Shared Posts
- Upcoming Conference – The Festival of Genomics & Biodata
- Gene trajectory inference for single-cell data by optimal transport metrics
- Upcoming Workshop – Advanced Topics in Single Cell RNA-Seq Analysis: Multiomics ATAC-Seq & RNA-Seq
- BAP-seq – bioorthogonal masked acylating agents for proximity-dependent RNA labelling
- Single-cell RNA-seq of the rare virosphere reveals the native hosts of giant viruses in the marine environment
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