Data Analysis

Newly aligned modENCODE RNA-Seq coverage data

rna-seq

Sue Celniker’s group has provided FlyBase with updated RNA-Seq coverage data for the modENCODE transcriptome datasets. The high-throughput sequencing reads from these experiments have been re-aligned to the new BDGP Release 6 reference genome assembly (NCBI accession GCA_000001215.4). This update ...

Read More »

miRNA Temporal Analyzer (mirnaTA) – for identifying differentially expressed microRNAs in temporal studies using normal quantile transformation

rna-seq

Many open-source bioinformatics tools to identify existing and/or discover novel miRNAs in next-generation sequencing (NGS) reads have become available. While miRNA identification and discovery tools are significantly improved, the development of miRNA differential expression analysis tools, especially in temporal studies, ...

Read More »

Bayesembler – bayesian transcriptome assembly

RNA-seq allows for simultaneous transcript discovery and quantification, but reconstructing complete transcripts from such data remains difficult. Here, researchers from the University of Copenhagen introduce the Bayesembler, a novel probabilistic method for transcriptome assembly built on a Bayesian model of ...

Read More »