Statistical Analysis

Can differential expression methods developed originally for conventional bulk RNA-seq data also be applied to single-cell RNA-seq?

rna-seq

University of Turku researchers compared five statistical methods to detect differentially expressed genes between two distinct single-cell populations. Currently, it remains unclear whether differential expression methods developed originally for conventional bulk RNA-seq data can also be applied to single-cell RNA-seq ...

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A comparison between PCA and hierarchical clustering

rna-seq

Advice from Charlotte Soneson, Qlucore Introduction Graphical representations of high-dimensional data sets are at the backbone of straightforward exploratory analysis and hypothesis generation. Within the life sciences, two of the most commonly used methods for this purpose are heatmaps combined ...

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