Transcriptome Assembly Tools

FRAMA – from RNA-seq data to annotated mRNA assemblies

rna-seq

Advances in second-generation sequencing of RNA made a near-complete characterization of transcriptomes affordable. However, the reconstruction of full-length mRNAs via de novo RNA-seq assembly is still difficult due to the complexity of eukaryote transcriptomes with highly similar paralogs and multiple ...

Read More »

SATRAP – SOLiD Assembler TRAnslation Program

rna-seq

SOLiD DNA sequences are typically analyzed using a reference genome, while they are not recommended for de novo assembly of genomes or transcriptomes. This is mainly due to the difficulty in translating the SOLiD color-space data into normal base-space sequences. ...

Read More »