Transcriptome Assembly Tools

De novo assembly of bacterial transcriptomes from RNA-seq data

A number of mature computational tools exist for both reference-based transcriptome assembly and de novo transcriptome assembly. However, most of the aforementioned tools were designed primarily for eukaryotic transcriptomes. Bacterial transcriptome assembly faces different challenges than eukaryotic transcriptome assembly. For ...

Read More »

Bayesembler – bayesian transcriptome assembly

RNA-seq allows for simultaneous transcript discovery and quantification, but reconstructing complete transcripts from such data remains difficult. Here, researchers from the University of Copenhagen introduce the Bayesembler, a novel probabilistic method for transcriptome assembly built on a Bayesian model of ...

Read More »