Automated laser-assisted single-cell sorting for cell functional and RNA sequencing
The world of cellular research moves quickly, and scientists are always looking for new methods to gain more precise insights into cell function and behavior. One critical aspect of this research involves sorting single cells for downstream analysis, such ...
SNIP – single-nuclei isolation and RNA sequencing of parasitic nematodes
Single-cell and single-nucleus transcriptomics have greatly advanced our understanding of how individual cells and tissues function in both healthy and diseased states. This technology allows scientists to study gene expression at the level of individual cells, giving them a ...
Isolating high-quality RNA for RNA-Seq from 10-year-old blood samples
RNA sequencing (RNA-Seq) has become an invaluable tool for research and diagnostics, helping scientists explore gene expression, identify disease markers, and develop new therapies. However, one of the challenges when working with RNA is its instability...
Adding transcriptomics to the bead-enabled accelerated monophasic multi-omics method is a step toward universal sample preparation
In modern biology, scientists are using powerful tools to study the complex molecules that make up living organisms. These molecules—proteins, lipids, metabolites, and RNA—are like pieces of a puzzle that fit together to form the bigger picture of how ...
Extraction of high quality and high yield RNA from frozen EDTA blood
For medical diagnostics and biomarker discovery, the ability to analyze gene expression from peripheral blood RNA holds immense potential. This technique offers valuable insights into systemic changes in...
Optimised RNA extraction method unlocks tough tissues for aquaculture research
Researchers at the University of Edinburgh have optimised a protocol that allows previously tough-to-reach genetic material in hard or frozen tissues to...
A versatile nuclei extraction protocol for single nucleus sequencing in non-model species
The use of single cell sequencing technologies has exploded over recent years, and is now commonly used in many non-model species. Sequencing...
GRAB-ALL – a high-throughput pipeline for DNA/RNA/small RNA purification from tissue samples for sequencing
High-throughput total nucleic acid (TNA) purification methods based on solid-phase reversible immobilization (SPRI) beads produce TNA suitable for both genomic and transcriptomic applications...
A novel cell membrane-associated RNA extraction method
Cell membrane-associated RNA (mem-RNA) has been demonstrated to be cell-specific and disease-related and are considered as potential biomarkers for disease diagnostics, drug delivery, and cell...
High purity and integrity RNA from human cell lines stored in liquid nitrogen for over 20 years
Biobanks are a key resource for obtaining human cell lines for biomedical research, including for drug development projects. Such projects often include...














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