Statistical Analysis

The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundance

rna-seq

The concordance of RNA-sequencing (RNA-seq) with microarrays for genome-wide analysis of differential gene expression has not been rigorously assessed using a range of chemical treatment conditions. Here a team led by researchers atuse at the US FDA comprehensive study design ...

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Multi-platform assessment of transcriptome profiling using RNA-seq in the ABRF next-generation sequencing study

rna-seq

High-throughput RNA sequencing (RNA-seq) greatly expands the potential for genomics discoveries, but the wide variety of platforms, protocols and performance capabilitites has created the need for comprehensive reference data. Here the authors describe the Association of Biomolecular Resource Facilities next-generation ...

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miRSeq – A User-Friendly Standalone Toolkit for Sequencing Quality Evaluation and miRNA Profiling

rna-seq

MicroRNAs (miRNAs) present diverse regulatory functions in a wide range of biological activities. Studies on miRNA functions generally depend on determining miRNA expression profiles between libraries by using a next-generation sequencing (NGS) platform. Currently, several online web services are developed ...

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