scONE-seq – A single-cell multi-omics method enables simultaneous dissection of phenotype and genotype heterogeneity from frozen tumors


Single-cell multi-omics can provide a unique perspective on tumor cellular heterogeneity. Most previous single-cell whole-genome RNA sequencing (scWGS-RNA-seq) methods demonstrate utility with intact cells from fresh samples. Among them, many are not applicable to frozen samples that cannot produce intact ...

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