From bench to bytes: a practical guide to RNA sequencing data analysis
A practical guide helps molecular biologists understand RNA sequencing data analysis, from quality control and normalization to differential expression and biological interpretation...
Unlocking the past – new method helps gain insights into old tissue
A book sits atop a table. Although it’s closed, its title, “Encyclopedia of Human Tissue,” promises untold secrets. Perhaps with this book, you can learn about different cell types and what they look like under normal conditions or conditions ...
Combining RNA sequencing and pathology images identifies glioblastoma subgroups linked to survival
Glioblastoma is an aggressive form of brain cancer known for its biological complexity. Even tumors that receive the same diagnosis can contain very different cells and molecular characteristics, which can influence how the disease progresses and how patients respond ...
NanoncRNA-seq – an rRNA-depleted full-length transcriptome strategy for identification of novel lncRNA isoforms
Long non-coding RNAs, or lncRNAs, are RNA molecules that do not produce proteins but play important roles in controlling how genes are turned on and off. They influence many cellular processes, including growth, development, and responses to environmental changes. ...
Validating RNA sequencing for reliable detection of plant viruses and viroids
High-throughput RNA sequencing is becoming an increasingly valuable tool for diagnosing plant diseases. Unlike traditional diagnostic methods that look for specific known pathogens, RNA sequencing can detect a wide range of viruses and viroids in a single test, including ...
New method reconstructs cell evolution from single-cell RNA sequencing data
Single-cell RNA sequencing has given scientists the ability to study the activity of thousands of individual cells at once. In cancer research, this technology helps reveal how cells differ from one another and how tumors evolve over time. However, ...
Multisite assessment of methods for cell preservation upstream of single-cell RNA sequencing
Single-cell RNA sequencing has become an important tool for understanding the diversity of cells within complex tissues. By examining gene expression in individual cells, researchers can identify cell types and molecular characteristics that are often hidden when analyzing large ...
New approach reveals how complete riboswitches control gene expression
Riboswitches are specialized RNA molecules that help bacteria regulate gene activity. These molecules can change their shape in response to specific chemicals, allowing them to turn genes on or off when needed. Scientists have learned a great deal about ...
RNA barcoding approach reveals previously unknown virus-host relationships
An interdisciplinary team of Rice University researchers has uncovered previously unknown relationships between bacteriophages — viruses that infect bacteria — and their bacterial hosts, offering a powerful new tool for next-generation microbiome engineering. Published in Nature Communications, the study utilizes ...
TAP-seq – targeted single-cell RNA and perturbation sequencing
Understanding what genes do inside cells is one of the biggest goals in biology. Researchers often study gene function by turning genes on or off and observing what changes happen in the cell. New technologies have made this possible ...
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Most Shared Posts
- Upcoming Conference – The Festival of Genomics & Biodata
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- Upcoming Workshop – Advanced Topics in Single Cell RNA-Seq Analysis: Multiomics ATAC-Seq & RNA-Seq
- BAP-seq – bioorthogonal masked acylating agents for proximity-dependent RNA labelling
- Single-cell RNA-seq of the rare virosphere reveals the native hosts of giant viruses in the marine environment
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