Technology

Anindya Dutta, MBBS, Ph.D., and colleagues have described a novel form of gene regulation that is altered in bladder cancer, leading to the boosting...

The subcellular localization of specific RNA molecules promotes localized cellular activity across a variety of species and cell types. The misregulation of this RNA targeting can result in developmental defects, and mutations in proteins that regulate this process are associated ...

Single-cell transcriptomic approaches have revolutionised the study of complex biological systems, with the routine measurement of gene expression in thousands of cells enabling...

Parkinson’s disease is marked by the death of dopamine-producing neurons in the brain — specifically in the substantia nigra, a structure...

Through single-cell RNA sequencing, a research group has successfully illuminated the characteristics of Myeloid immune cells in coronary plaque, which causes acute coronary syndrome (this term includes...

Stanford University School of Medicine researchers have developed NEAT-seq (sequencing of nuclear protein epitope abundance, chromatin accessibility and the transcriptome in single cells), enabling...

A new software tool makes it easier to study relationships between a host, its microbiome and pathogens like HIV or SARS-CoV-2. Researchers...

In a series of studies published in Cell Press journals, STOC members used the spatially resolved transcriptomics technology Stereo-seq, developed by BGI-Research, to produce spatiotemporal cellular...

“Pytheas” app created by a team at Scripps Research allows scientists to identify and quantify modified RNA molecules more easily than ever. Scientists at Scripps Research have unveiled a new software tool for studying RNA (ribonucleic acid) molecules, which have ...

Due to the overall high costs, technical replicates are usually omitted in RNA-seq experiments, but several methods exist to generate them artificially...