Combination of nucleic acid nanotechnology and cryo-EM gives unprecedented insights into the structures of large and small RNAs, enabling...
Read More »Asteria© single-cell RNA-seq kit and companion Cytonaut© analysis software are now commercially available
Researchers worldwide can now order the Asteria© single-cell RNA-seq kit to profile up four samples of 10,000 individual cells Genomics researchers can now perform straightforward, instrument-free single-cell cDNA preparation at their workbench to achieve high mRNA capture and gene sensitivity ...
Read More »Single-cell analysis reveals older men with high body-mass index have more sperm cell irregularities
Single-cell analysis of autopsied human testes suggests that abnormalities associated with aging sperm cells might be exacerbated by elevated...
Read More »An optimized skin tissue dissociation protocol for single-cell RNA sequencing analysis
Researchers from the University of Zurich present an optimized dissociation protocol for preparing high-quality skin cell suspensions for in-depth single-cell...
Read More »Does autism begin in the womb?
Autism (autism spectrum disorder) is a developmental neurological disorder that remains largely unexplored despite the rapidly increasing number of patients. Immune abnormalities, now considered the cause of many diseases, also play an important role in the development of autism. Brain ...
Read More »RiboRid – A low cost, advanced, and ultra-efficient method to remove ribosomal RNA for bacterial transcriptomics
RNA sequencing techniques have enabled the systematic elucidation of gene expression (RNA-Seq), transcription start sites (differential RNA-Seq), transcript 3′ ends (Term-Seq), and post...
Read More »R code and downstream analysis objects for the scRNA-seq atlas of normal and tumorigenic human breast tissue
Breast cancer is a common and highly heterogeneous disease. Understanding cellular diversity in the mammary gland and its surrounding micro-environment across different states can...
Read More »Enhanced recovery of single-cell RNA-sequencing reads for missing gene expression data
Droplet-based 3’ single-cell RNA-sequencing (scRNA-seq) methods have proved transformational in characterizing cellular diversity and generating valuable hypotheses throughout biology. Researchers from the University of Texas Southwestern Medical...
Read More »Researchers share insights about the mechanisms of human embryo and create method to develop transcriptionally similar cells in tissue culture
Blood-forming stem cells found in bone marrow are the life-saving component used in bone marrow transplants. However, suitable donors often cannot be found in many cases. This study reveals how the human embryo develops the precursor to blood...
Read More »Lexogen Introduces CORALL RNA-Seq V2 – a fast and flexible whole transcriptome RNA-Seq Library Prep Kit.
Lexogen, a transcriptomics and Next-Generation Sequencing company today announced the release of the new CORALL RNA-Seq V2 whole transcriptome library prep kit. Whole-transcriptome analysis with RNA sequencing (RNA-Seq) is at the cutting edge of NGS capabilities and allows to determine ...
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