In the rapidly advancing field of genomics, Single-Cell RNA Sequencing (scRNA-seq) has emerged as a transformative technology, allowing us to gain unprecedented insights into the intricacies of...
Read More »Getting started with RNAseq – Transforming raw reads into biological insights
RNA sequencing (RNAseq) is a powerful technique for investigating gene expression in biological samples. Processing and analysing RNAseq data...
Read More »ScRNAPip – A systematic and dynamic pipeline for single-cell RNA sequencing analysis
With the advancement of sequencing technology, cell separation, and whole-genome amplification techniques, single cell technology for genome sequencing is emerging gradually. In comparison to traditional genome sequencing at the multi-cellular level, single-cell sequencing can not only measure the gene expression ...
Read More »Why are researchers going beyond mutations to study cancer?
Cancer is an incredibly complex system, and researchers in Toronto have found that mutations alone are not enough to fully understand diverse cancers. Each layer of regulation – genome...
Read More »RNA Sequencing: Workflow Recommendations
NGS Bootcamp – SUNY Albany – We recommend using an input amount of 100–150 pg amplified DNA. Small genome, amplicon, & targeted gene panel sequencing. Exome, transcriptome, & whole-genome…
Read More »Establishing quality control metrics for B cell receptor analysis using the next generation sequencing technologies
With the rapid development and adaptation of next-generation sequencing (NGS) technologies, we have the unprecedented opportunity to interrogate many fundamental and transformative questions...
Read More »How can we use RNA sequencing to figure out how a drug works?
RNA-Seq is such a powerful tool! In this video I discuss how using the awesome power of RNA sequencing we can narrow down the potential mechanism of a novel drug. Learning objectives: Explain the challenges associated with elucidating the mechanisms ...
Read More »Bulk RNA-Seq data analysis using CLC Genomics Workbench
This workshop briefly introduces techniques, platforms, and methods used in bulk RNA-Seq experiments, followed by a software demonstration using the HSLS-licensed CLC Genomics Workbench...
Read More »Comparing TempO-seq and RNA-seq mRNA data sets
There are multiple technological platforms available for quantifying mRNA levels to use for transcriptomics studies. With the increase in mRNA expression data generated using TempO-seq, it is...
Read More »Study highlights the power of single-nucleus RNA sequencing and spatial transcriptomics to uncover facets of disease biology
Researchers applied single-nucleus RNA sequencing and spatial transcriptomics to identify potential therapeutic targets in brain metastases. In patients with renal cell carcinoma, brain metastases had...
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