Benchmarking RNA sequencing for more accurate alternative splicing analysis
RNA sequencing benchmarking across 42 laboratories identifies data quality, sequencing depth, and bioinformatics choices that improve alternative splicing and isoform analysis...
RNA Sequencing identifies new tick-borne virus that causes flu-like illness
RNA sequencing identified the novel tick-borne ALTNV in febrile patients in China, helping distinguish infections that can resemble Dabie bandavirus disease...
Small RNA sequencing reveals regulatory roles for sdRNAs in acute myeloid leukemia
Small nucleolar RNAs, or snoRNAs, are short RNA molecules best known for helping modify and process other RNAs inside cells. Researchers have also discovered that snoRNAs can be cut into even smaller fragments called snoRNA-derived RNAs, or sdRNAs. The ...
POND-seq enables non-destructive RNA sequencing in living cells
RNA sequencing is widely used to measure gene activity, but most methods require cells to be broken open or fixed before their RNA can be collected. This means researchers usually get only a single snapshot of gene expression from ...
Worm’s radical transformation shows metamorphosis can change the functions of cells
A squishy worm that starts its life as something of a floating head in the Pacific Ocean is changing what scientists know about metamorphosis at the cellular level.Unlike humans, about 80% of animal species undergo metamorphosis, a stepped development ...
New method allows scientists to follow gene activity over time in the same cells
Live-cell RNA sequencing uses engineered virus-like particles to repeatedly sample transcriptomes without destroying cells, enabling researchers to track gene expression changes over time...
Single-cell and single-embryo RNA sequencing
Single-cell and single-embryo RNA sequencing enables detailed analysis of gene expression and cell identity during the earliest stages of embryonic development...
RNA sequencing reveals functional chimeric mRNAs in mammalian immunity
Direct RNA sequencing revealed thousands of chimeric mRNAs in mammalian cells, uncovering previously unknown proteins with roles in immunity, inflammation, and potential drug discovery...
Deep learning improves microRNA target prediction from sequence
MicroRNAs, or miRNAs, are small RNA molecules that help control gene expression. They work by guiding Argonaute proteins to specific RNA targets, where they can reduce the production of proteins from those genes. Predicting which RNAs a miRNA will ...
Atlas of the brain’s striatum could guide researchers to new drug treatments
A new study reveals insights into populations of neurons affected by Huntington’s disease, schizophrenia, addiction, and other disorders. A region of the brain called the striatum is critical for many cognitive and motor functions, including decision-making, control of movement, ...
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Most Shared Posts
- Upcoming Conference – The Festival of Genomics & Biodata
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- Upcoming Workshop – Advanced Topics in Single Cell RNA-Seq Analysis: Multiomics ATAC-Seq & RNA-Seq
- BAP-seq – bioorthogonal masked acylating agents for proximity-dependent RNA labelling
- Single-cell RNA-seq of the rare virosphere reveals the native hosts of giant viruses in the marine environment
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