Publications

scRNA-seq has become a widespread technique within the life sciences but analysis of the data has previously required an in-depth understanding of complex bioinformatics techniques...

RNA sequencing (RNA-seq) is a powerful and increasingly prevalent method to characterize and quantify the transcriptome. Ribosomes are extremely abundant, however, and approximately 80% of total RNA is ribosomal RNA (rRNA). Therefore, to detect and quantify less abundant yet biologically ...

Current bioinformatics workflows for PIWI-interacting RNA (piRNA) analysis focus primarily on germline-derived piRNAs and piRNA-clusters...

Single-cell RNA analysis has been integrated with spatial protein profiling to create a single–cell type map of human tissues...

A new method that analyzes how individual immune cells react to the bacteria that cause tuberculosis could pave the way for new vaccine strategies against this deadly disease, and provide insights into fighting other infectious diseases around the world. The ...

The in vivo phenotypic profile of T cells reactive to severe acute respiratory syndrome (SARS)-CoV-2 antigens remains poorly understood. Conventional methods to detect antigen-reactive T cells require in...

St. Jude Children’s Research Hospital study highlights the power of comprehensive whole genome, whole exome and RNA sequencing to...

Communication with bacteria deeply impacts the life history traits of their hosts. Through specific molecules and metabolites, bacteria can promote short- and long-term phenotypic and behavioral...

Researchers from HSE University have discovered nucleotide sequences characteristic of microRNA isoforms (microRNAs with errors). The discovery will help predict errors in microRNA behaviour and...

Tumor heterogeneity—the complex microenvironment of different cell subpopulations within a single tumor—remains a major challenge...