Its not just about the DNA

Looking Beyond DNA Defects to Characterize Cancer from MSKCC By Julie Grisham Summary Advances in gene sequencing have revealed much information on the genetic mutations that can lead to cancer. But technologies that look only at changes in tumor DNA ...

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Mapping the cell response to fluid flow using RNA-Seq


Bone adaptation to mechanical loading is regulated via signal transduction by mechano-sensing osteocytes. Mineral-embedded osteocytes experience strain-induced interstitial fluid flow and fluid shear stress, and broad shifts in gene expression are key components in the signaling pathways that regulate bone ...

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