Review Publications

Putting transcriptomics in its place

rna-seq

from Nature Reviews Genetics by Darren J. Burgess A recent focus of transcriptomics is to supplement gene expression data with spatial information on cellular or tissue context in order to obtain a greater understanding of physiological gene regulatory processes. A ...

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Insights from RNA Sequencing

rna-seq

The human transcriptome comprises >80 000 protein-coding transcripts and the estimated number of proteins synthesized from these transcripts is in the range of 250 000 to 1 million. These transcripts and proteins are encoded by less than 20 000 genes, suggesting extensive regulation ...

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Single-Cell Sequencing Technologies – Current and Future

rna-seq

Intensively developed in the last few years, single-cell sequencing technologies now present numerous advantages over traditional sequencing methods for solving the problems of biological heterogeneity and low quantities of available biological materials. The application of single-cell sequencing technologies has profoundly ...

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