REDalign – accurate RNA structural alignment using residual encoder-decoder network
RNA molecules are essential for various biological processes, and studying them helps scientists understand how cells function. A key part of this research involves examining the "secondary structures" of RNA, which are specific shapes RNA molecules fold into due ...
CTPAD – an interactive web application for comprehensive transcriptomic profiling in allergic diseases
Allergic diseases, such as asthma and hay fever, are not just simple allergies; they are complex conditions that can affect multiple organs and involve chronic inflammation. Researchers have been investigating the role of gene expression—how genes are turned on ...
WebAtlas pipeline for integrated single-cell and spatial transcriptomic data
Single cell RNA-sequencing (scRNA-seq) and spatial transcriptomics (ST) are powerful techniques that offer complementary insights into tissues. scRNA-seq allows scientists to analyze the gene expression of individual cells...
sCIRCLE – an interactive visual exploration tool for single cell RNA-Seq data
A research team from HIRI and THWS develops a tool for visualizing single-cell data Modern cutting-edge research generates enormous amounts of...
Benchmarking second-generation methods for cell-type deconvolution of transcriptomic data
In silico cell-type deconvolution from bulk transcriptomics data is a powerful technique to gain insights into the cellular composition of complex tissues. While first-generation methods used...
Introducing Alzheimer DataLENS: a powerful tool for Alzheimer’s Disease research
Alzheimer's disease (AD) is a complex and devastating condition that affects millions of people worldwide. Researchers are tirelessly working to understand its underlying mechanisms and find effective treatments. Recent breakthroughs in Alzheimer’s research are increasingly driven by advanced "omics" technologies, ...
betAS – intuitive analysis and visualisation of differential alternative splicing using beta distributions
Next generation RNA sequencing allows alternative splicing (AS) quantification with unprecedented resolution, with the relative inclusion of an alternative sequence in transcripts being commonly quantified...
RiboGalaxy – A Galaxy-based web platform for ribosome profiling data processing – 2023 Update
Ribosome profiling (Ribo-Seq) captures a “snapshot” of ribosomes’ locations at the entire transcriptome of a cell at sub-codon resolution providing insights...
Establishment of a hybridoma sequencing pipeline for sequencing of antibody variable regions
The Neuroscience Monoclonal Antibody Sequencing Initiative (NeuroMabSeq) is a concerted effort to determine and make publicly available hybridoma-derived sequences of monoclonal antibodies (mAbs) valuable to neuroscience research. Over 30 years of research and development efforts including those at the UC ...
NORMSEQ – a tool for evaluation, selection and visualization of RNA-Seq normalization methods
RNA-sequencing has become one of the most used high-throughput approaches to gain knowledge about the expression of all different RNA subpopulations. However, technical artifacts, either introduced during library preparation and/or data analysis, can influence the detected RNA expression levels. A ...














Stay Connected