Expert highlights the clinical utility of RNA sequencing methods in cancer


Kevin Halling, MD, PhD, a consultant in the Division of Laboratory Genetics and Genomics and Department of Laboratory Medicine and Pathology at the Mayo Clinic, discussed the clinical utility of RNA-sequencing methods in patients with cancer at the Association for Molecular Pathology (AMP) Annual Meeting and Expo. Halling says RNA sequencing is a very powerful technique. According to Halling, these methods can be used to detect not only gene fusions in patients with cancer, but RNA sequencing can also detect point mutations and small indels. Additionally, pathologists can use RNA sequencing techniques to measure gene expression in their patients as well. The role of RNA sequencing is evolving in many labs as a tool for detecting gene fusions, but the clinical utility will continue to expand, Halling concludes. RNA sequencing is important because so much information can be gained from 1 test. This provides a lot of value for the money spent on a single test. For more resources and information from the AMP Annual Meeting & Expo: https://www.targetedonc.com/conference/amp-2019

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