At Boston Children’s Hospital, the quality of our care – and our inclusive hospital working environment – lies in the diversity of our people. With patients from local communities and 160 countries around the world, we’re committed to reflecting the spectrum of their cultures, while opening doors of opportunity for our team. Here, different talents pursue common goals. Voices are heard and ideas are shared. Join us, and discover how your unique contributions can change lives. Yours included.
Research Computing at Boston Children’s supports basic, translational, and clinical research by providing researchers with access to digital tools and technologies. Our computing environment consists of high-performance computing clusters, virtual machines, PetaByte-scale high-performance storage and cloud platforms. We work with BCH scientists to develop solutions in support of cutting-edge research ranging from lattice light-sheet microscopy to CryoEM, genomics, and informatics. The role will be responsible for providing routine as well as leading-edge support for researchers who have single-cell RNA-seq, single-cell ATAC-seq, spatial transcriptomics, bulk RNA-seq, ChIP-seq and methylation data to investigate human genetics and cortical development and other human and mouse diseases as well as with other pediatric scientists at BCH. The primary responsibilities will be building pipelines for the analysis, integration and sharing of these data. The candidate will analyze, integrate different types of next-generation sequencing data and interpret the results and will have the opportunity to publish high-profile papers with prominent authorship depending on the intellectual contribution. They should have enthusiasm for developing collaborative relationships and a desire to foster the use of bioinformatics data in research studies.
The Bioinformatics Scientist shall be responsible for:
- Providing computational support services to Boston Children’s Hospital scientists and clinicians by applying a wide range of bioinformatics tools, methods and technologies.
- With supervision and direction, completing assignments in the required timeframe while consistently adhering to standard operating procedures and best practices; adapting to a changing environment, resolving problems associated with assignments and seeking supervisor assistance when needed.
- Participating and/or co-leading Research Computing projects with other members from the BCH research community; setting goals and objectives for projects and demonstrating achievement of those goals and objectives.
- Training staff and researchers; effectively tailoring presentations; developing, implementing and maintaining knowledge management systems.
- Creating or contributing to a range of compelling communications (e.g. PowerPoint presentations, e-mails, memos, scientific presentations, and publications) that clearly deliver content; preparing communications appropriate for management and internal distributions.
To qualify you must have:
- Minimum of 4-year Bachelor’s degree in STEM. Minimum of one year of advanced bioinformatics experience. Preference for candidates with a Ph.D. in Bioinformatics, Computational Biology or related.
- Extensive knowledge of the use of bioinformatics computations in high-performance computing environments, including open-source bioinformatics software and pipelines to support diverse bioinformatics analyses such as single-cell RNA-seq, bulk RNA-seq, ChIP-seq, methylation, etc.
- Extensive knowledge of technologies used in support of biomedical research, such as programming languages (R and Python), databases (SQL), version control (Git), scientific workflow tools and high-performance computing clusters. Cloud computing tools would be a bonus.
- Strong publication record. Ability to effectively convey messages through written communication that are tailored to target audiences; meeting discussions and one-on-one verbal communications are clear and effective; ability to conduct effective meetings, to present in departmental and hospital forums and to develop training instructions and manuals.