The Bloomberg Kimmel Institute is recruiting an individual to lead single cell RNA sequencing and TCR sequencing analytics as a Senior Research Assistant. This person will be active in the data pre-processing stages as well as analysis and interpretation of results.
Eligible candidate will be involved in designing and developing analysis plans to address biological hypotheses in our bank of single cell data, mostly acquired from lung cancer patients treated with checkpoint blockade. The candidate will interact daily with data analysts within the Institute, as well as Immunologists, Genomics experts, and clinicians. This position requires collaboration with clinical and scientific investigators in research/study design, data analysis plans, algorithm development, grant applications, and preparation of presentations and publications.
The candidate should work independently and in collaboration with faculty to solve problems posed by the clinical and laboratory investigators along the study design, data generation, collection and management process; interaction with bioinformatic experts, biostatistician program developers, computational scientists, health informatic experts as well as postdoc fellows from the Sidney Kimmel Comprehensive Cancer Center and the Bloomberg School of Public Health on our immunogenomic data mining initiatives with the goal of translating these findings into therapeutic modalities for cancer patients.
Specific Duties & Responsibilities:
- This position will be responsible for the data management and basic bioinformatics analysis under the supervision of the PI and Programmer Analyst.
- Facilitate acquisition and transfer of high dimensional genomic datasets within Johns Hopkins and between outside institutions
- Clean data by coding missing data, fixing or deleting miscoded data, transforming variables into more useful formats, and annotating the data in a proper way.
- Use descriptive statistics to help characterize and summarize datasets
- Generate plots representing dimensionality reduction
- Collaborate with clinical and scientific investigators in BKI to propose ideas for new projects, design research, develop data plan, and prepare analyses with general direction from investigators
- Apply different technical approaches to visualize the data and prepare publication-quality tables and graphs based on valid analysis
- Identify potential data problems from analytic queries and bring them to the attention of the team.
- Demonstrate progress in ability to multi-task and manage time spent working with individual faculty members and on specific projects
- Participates in regularly schedule meetings with study investigators and team. Prepares progress reports as needed. Maintain appropriate systems for data organization.
- Perform quality assurance on data
- Produce descriptive reports, including tables and graphs
- Create research databases as needed, merging data, defining new variables
- Work with external and internal investigators to create datasets needed for analytic projects
- Work collaboratively with investigators, analysts and study coordinators
- Implement code to perform basic statistical, epidemiological and informatic analysis for research questions, manuscripts and contract/grant submissions
- Able to work collaboratively in a team environment with a high degree of initiative and self-motivation
- Completes minimum requirement for continuing educational units. Is knowledgeable of and complies with Good Clinical Practices, ICH Guidelines and SKCCC Clinical Research Office policies.
Minimum Qualifications (Mandatory):
- BA/BS Degree in Biological/Social Sciences/Data Science/Public Health or other appropriate discipline required. Advanced Degree (MHS, M.S.) may substitute for experience.*
- Minimum of 2 years’ experience in data management and analysis for research protocols is required.
- Knowledge of research methodology and working knowledge of computers required.
- Highly effective verbal communication and interpersonal skills required.
- Must be able to independently assimilate and evaluate research data.
- Must have excellent communication skills and work well in a group setting.
* JHU Equivalency Formula: 18 graduate degree credits may substitute for one year of experience.
** Applicants who do not meet the posted requirements but are completing their final academic semester/quarter will be considered eligible for employment and may be asked to provide additional information confirming their academic completion date.
Special Knowledge, Skills & Abilities:
- Proficiency with R or other programing languages required.
- Excellent organizational skills required.
- Excellent attention to detail skills required.
- Ability to manage multiple and competing priorities.
- Must have excellent time management skills.
- Must have excellent oral and written communication skills.
Classified Title: Sr. Research Assistant
Starting Salary Range: $39,310 – $54,060 annually (commensurate with experience)
Employee group: Full Time
Schedule: M-F 9am-5pm
Exempt Status: Exempt
Location: Hybrid/School of Medicine Campus
Department name: Cancer Immunology/GI Clinical Research
Personnel area: School of Medicine
The successful candidate(s) for this position will be subject to a pre-employment background check.
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