Get Rid of the Noise – Targeted Depletion Approach for RNA-Seq

In this webinar, researchers from NuGEN describe a novel method for targeted depletion of unwanted transcripts in RNA-Seq libraries. The proprietary Insert Dependent Adaptor Cleavage (InDA-C) technology employs customized probes to target specific transcript species for exclusion in the final RNA-Seq library. Unlike methods that use hybridization-mediated pull-down strategies to deplete unwanted RNA species prior to cDNA synthesis, the InDA-C method depletes targeted transcripts from RNA-Seq libraries, avoiding off-target mRNA cross-hybridization events that can potentially introduce bias.