Changes in gene expression levels can reflect the effects of genetic variation, environment, and disease processes or treatments. RNA-Seq drives the differential expression for this complex disease research. Utilizing RNA-seq driven techniques such as transcriptome-wide association studies (TWAS) has allowed researchers to integrate GWAS and eQTL data to help associations between predicted expression and traits.
Illumina’s new Illumina Gene Expression and Regulation Research E-Book takes a comprehensive look at different RNA-Seq and Methylation methodologies and publications. It includes background information on NGS and Microarrays, in addition to introductory information on different modalities that can be utilized for Gene Expression Studies.
For research use only. Not for use in diagnostic procedures.