Researchers have identified the major molecular mechanism behind the transition between chronic and acute P. aeruginosa infections. Pseudomonas aeruginosa clumps grown in synthetic cystic fibrosis sputum People with weakened immune ...
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Establishing quality control metrics for B cell receptor analysis using the next generation sequencing technologies
With the rapid development and adaptation of next-generation sequencing (NGS) technologies, we have the unprecedented opportunity to interrogate many fundamental and transformative questions...
Read More »TORNADO-seq – a protocol for high-throughput targeted RNA-Seq-based drug screening in organoids
Organoids are 3D ex vivo cell aggregates derived from primary tissue and shown to closely recapitulate tissue homeostasis. Organoids deliver certain advantages compared to 2D cell lines and...
Read More »UC Irvine neuroscientists develop ‘meta-cell’ to move single-cell transcriptomics forward
Technologies called transcriptomics that study sets of RNA within organisms enable scientists to understand what each cell does. However, the question of how particular genes work within a solo cell, a process known as single-cell genomics...
Read More »PHYTOMap – multiplexed single-cell 3D spatial gene expression analysis in plant tissue
Retrieving the complex responses of individual cells in the native three-dimensional tissue context is crucial for a complete understanding of tissue...
Read More »Different genes are expressed at different stages during pregnancy
Findings provide a “normal reference”, describing biological changes that occur in the healthy mother’s blood during different trimesters of pregnancy Using RNA sequencing and computational methods to...
Read More »The promise of single-cell rna sequencing to redefine the understanding of Crohn’s Disease fibrosis mechanisms
Crohn’s disease (CD) is a chronic inflammatory bowel disease with a high prevalence throughout the world. The development of Crohn’s-related fibrosis, which leads to strictures in the gastrointestinal tract...
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Data Scientist for Bioinformatics and Computer Biology
Job Description: Ph.D. in Bioinformatics, Computational Biology, Computer Science, Biomedical Engineering, Computer Engineering, Genetics/Genomics or related field. Experience with ‘omics platform output. Experience with biological datasets and next generation sequencing ...
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Job available – Data Scientist for Bioinformatics and Computer Biology
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Featured RNA-Seq Job – Bioinformatician-Computational Biologist
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NERVSPAN PhD position at Single Cell Discoveries
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Featured RNA-Seq Job – Team Lead Spatial Transcriptomics
Industry News
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Do you wonder what 10X data looks like on the newest Illumina sequencer?
Single-cell analysis can help tease apart heterogeneity in complex cell populations, distinguishing cell types and revealing dynamic cell states. The 10x Genomics Chromium Single Cell Multiome ATAC + Gene Expression prepares sequencing...
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Data visualisation: past, present and future
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NVIGEN pioneers breakthrough in high-resolution tissue RNA sequencing with magnetic nanoparticle capture
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Advancements in genome sequencing propel global RNA sequencing market growth to 2030
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Fluent BioSciences awarded NIH SBIR grant to revolutionize single cell analysis