The Brain Transcriptome International Review of Neurobiology – Volume 116, Pages 2-352 (2014) Chapter One – Introduction to Sequencing the Brain Transcriptome Pages 1-19 Robert Hitzemann, Priscila Darakjian, Nikki Walter, ...
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Incorporating alternative splicing and mRNA editing into the genetic analysis of complex traits
The nomination of candidate genes underlying complex traits is often focused on genetic variations that alter mRNA abundance or result in non-conservative changes in amino acids. Although inconspicuous in complex ...
Read More »Official release of TeloPrime Full-Length cDNA Amplification Kit
TeloPrime enables the amplification of full-length cDNA with extreme stringency based on a new innovative technology. It allows more faithful tagging of full-length RNA transcripts that are both capped and ...
Read More »RVboost: RNA-Seq variants prioritization using a boosting method
RNA-Seq has become the method of choice to quantify genes and exons, discover novel transcripts, and detect fusion genes. However, reliable variant identification from RNA-Seq data remains challenging due to ...
Read More »Comprehensive Analysis of Alternative Splicing by Strand-Specific RNA-Seq
Digitalis purpurea (D. purpurea) is one of the most important medicinal plants and is well known in the treatment of heart failure because of the cardiac glycosides that are its ...
Read More »MIRPIPE – quantification of microRNAs in niche model organisms
MicroRNAs represent an important class of small non-coding RNAs regulating gene expression in eukaryotes. Present algorithms typically rely on genomic data to identify miRNAs and require extensive installation procedures. Niche ...
Read More »Introduction to RNA-Seq and its Applications to Drug Discovery and Development
The research and development (R&D) process in modern drug discovery and development is a challenging task. One of the reasons is because the biological system is complex. There are 20,000–25,000 ...
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