Post-doc position available – RNA-seq bioinformatics

University of Toronto Scarborough
Location: Toronto, Ontario Canada
Job Type: Postdoctoral
Degree Level Required: PhD

Position Overview:

We are looking to hire a postdoctoral fellow interested in working on a collaborative project to call RNA modifications from Oxford Nanopore Sequencing data. Interested candidates with a doctoral degree in any areas of biology relating to transcriptomics, bioinformatics, and RNA biology are encouraged to apply. This position offers an exciting opportunity to understand the role of RNA modifications in development, behavior, and/or health and disease. Opportunities for expanding the position into wet lab workflows (ONT sequencing) and wet lab method development and optimization are available.

Responsibilities:

  • The selected candidate will work on a collaborative project to develop an analysis pipeline to call RNA modifications using Oxford Nanopore Sequencing.
  • Benchmark existing methods for calling modifications.
  • Collaborate closely with Project PIs to develop pipelines for RNA modification analysis.
  • Participate in regular meetings with the research team to share progress and insights, discuss findings, and refine the research objectives and methodologies.
  • Data Management: Organize and maintain a comprehensive sequence database with associated metadata
  • Analyze and synthesize research findings from various sources to identify key trends, data types, methods, and gaps in the existing literature.
  • Experience with python/R, a workflow language (snakemake or nextflow), and/or unix environment is preferred.

Qualifications:

  • PhD degree in a relevant field (e.g., biology, bioinformatics, RNA biology, transcriptomics, computer science, or a related discipline).
  • Experience in bioinformatics (genomics, transcriptomics) is required.
  • Experience with Oxford Nanopore Sequencing is a plus.
  • Experience with developing RNA sequencing analysis pipelines is a plus.
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