Post-Doc Position in Systems Biology and Modeling of High-Throughput Data – Freiburg, Germany

The group “Systems Biology of the Cellular Microenvironment” at the Institute for Molecular Medicine and Cell Research (IMMZ), U, is offering


one Post-Doc position in Systems Biology and Data Analysis

for three years, starting as soon as possible. Salary will be according to E13 TV-L.
The position within the joint experimental and theoretical systems biology group, headed by Dr. Dr. Melanie Börries and Dr. Hauke Busch, will deal with bioinformatic analysis and modelling of time-resolved microarray and RNA-Seq data. In combination with proteome and high-throughput imaging data the goal is to develop multi-scale models for the simulation and control of microspore derived embryo formation in plants. The positions are part of the newly established BMBF research consortium Microsystems (“BioSystems analysis of microspores to improve industrial plant embryo production”).

We require
• a degree in bioinformatics, physics, mathematics or related areas,
• prior knowledge in high-throughput data analysis and modelling of biological systems (not necessarily plants),
• an interest in crossing research borders to establish new experimental and mathematical, approaches in systems biology,
• the ability to communicate with other scientists at the interface between theoretical and experimental research,
• programming skills in either R, Matlab, C or equivalent.

We offer
• a truly interdisciplinary research environment with experiment and theory within one group,
• possibility to cross between dry- and wet-lab, plant and mammalian cell biology,
• advanced training in systems biology methods and their combination,
• possibilities for supervision of master and/or PhD students.

Our group focuses on the development and verification of dynamic computer- and cell culture-models to predict and control cellular decisions like proliferation, differentiation or apoptosis. Models incorporate biological mechanisms spanning different time- and length scales from protein signaling to multi-cell communication and tissue/tumor development. Applications will range from wound healing, cell aging to plant development (
We are looking forward to your applications including a CV, previous research experience, list of publications (if applicable) as well as references, which should be sent via e-mail or conventional mail to Melanie Börries ( or Hauke Busch (

Women are explicitly invited to apply. Handicapped persons will be preferred in case of equal qualification.