We are looking to recruit an experienced Bioinformatician to join a successful international team studying the mechanisms of gene expression in the immune system. The laboratory consists of five groups studying various aspects of immunology including the impact of ageing on immunity. The post holder will take a lead role in the development of methods to analyse the transcriptome of lymphocytes where available tools do not suffice to address the relevant biological questions. There will be an emphasis on the analysis of the dynamics of gene expression, identification of different mRNA isoforms and the discovery of novel transcripts and open reading frames. In addition to leading their own project the applicant will assist others with the design and analysis of experiments involving next generation sequencing.
The successful applicant will be a PhD level bioinformatician with experience in the design and analysis of experiments that use next generation sequencing to gain information on gene expression mechanisms. Experience in both the development of novel analysis tools as well as using existing packages for high throughput sequence analysis is essential.
Some examples of our work can be found below.
For more information on our science please visit our website (www.babraham.ac.uk)
- Galloway, A., Saveliev, A., Łukasiak, S., Hodson, D.J., Bolland, D., Balmanno, K., Ahlfors, H., Monzón-Casanova, E., Ciullini-Mannurita, S., Bell, L.S., Andrews, S. R., Díaz-Muñoz, M.D., Cook, S. J., Corcoran, A. and Turner M. (2016) RNA binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence. Science 352:45. [abstract]
- Carr EJ, Dooley J, Garcia-Perez JE, Lagou V, Lee JC, Wouters C, Meyts I, Goris A, Boeckxstaens G, Linterman MA, Liston A. (2016) The cellular composition of the human immune system is maintained in multiple stable equilibriums shaped by age and cohabitation. Nature Immunology 17(4):461-8.[abstract]
This position is available immediately. Funding for this post is available for three years in the first instance but potentially convertible to an indefinite appointment.
Informal enquiries may be made to Dr Martin Turner [email protected]
Starting salary is £39,005 per annum to £43,342 per annum depending on experience.
On applying please quote reference MT-BIOST2-LTC.
Closing date for completed applications Thursday 18th August 2016
Interviews will take place on 24th and/or 25th August 2016