Post-doc positions available – Functional RNAomics

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The Functional RNAomics laboratory at the Faculty of Medicine and Health Technology, Tampere University studies gene regulation via RNA processing. By determining how RNA regulation is orchestrated in different cell types, we aim to crack the cellular RNA code and gain critical insights into how aberrations in the RNA machinery result in genetic disorders and cancer. RNA is emerging as a powerful and easily adaptable therapeutic molecule as exemplified by the rapid development of effective mRNA vaccines but a detailed knowledge of RNA regulation in cells is a prerequisite to realise the full potential of RNA-based therapeutic and diagnostic development. We integrate cell biology approaches with mechanistic studies, global mapping of RNA repertoires, RNA binding protein interactions and proteomics profiles to reveal the functional role of RNA-protein complexes in different cell lineages and in disease.

Job description

We are looking for two post-doctoral researchers on full- or part-time basis:

1. The postdoctoral researcher in cell and molecular biology will conduct experimental research involving advanced molecular biology techniques including sample preparation for short-read and long-read RNA sequencing, cell and organoid cultures, and various biochemistry methods. The work involves experimental planning, detailed recording of data, data analysis and reporting of results.
2. The post-doctoral research in bioinformatics will analyse a range of large-scale datasets including short-read RNA sequencing, long-read direct RNA sequencing and proteomics data. The work includes the application of existing data analysis pipelines as well as the development of new computational methods. It also involves experimental planning, detailed recording of data and reporting of results.

Requirements

The positions are mostly intended for recently graduated researchers, so that they may gain further experience and advance their careers. You should have a PhD degree in biochemistry, genetics, molecular biology, bioinformatics/computational biology or a related subject area. We expect a competence to pursue independent scientific work. You should be fluent in spoken and written English and have a solid experience either in (1) cell and molecular biology or (2) computational biology/bioinformatics. Skills in both wet and dry lab research are considered an advantage.

You should be able to communicate with experimental and computational biologists as a member of a multidisciplinary team. We appreciate experience of studying or working abroad and contacts to international research community. We are looking for versatile and independent researchers with experience in the closely related area of the positions. It is expected that you will be able to contribute to the supervision of M.Sc. and Ph.D. students. Please be prepared to provide a proof of your merits when requested.