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Job Description Summary

The Reiner Lab is seeking a motivated and experienced Research Specialist D to join our team investigating behavioral, pharmacological, and intersectional genetic approaches coupled with neural multiomics and bioinformatics analysis in preclinical animal models. Our research addresses critical questions related to psychiatric diseases, substance use disorders, and disorders involving feeding and energy balance.

Responsibility Breakdown:

• Conduct experiments involving single-cell/nuclei RNA sequencing and epigenetic profiling.
• Execute both short-read (Illumina) and long-read (Oxford Nanopore Technologies – ONT) genetic sequencing protocols.
• Perform bioinformatics analyses and interpretation of sequencing data, including data from single-cell and multiomic experiments.
• Engage in animal handling and husbandry; perform animal behavioral assays as required.
• Carry out molecular biology experiments, including RNA/DNA extraction, PCR, qPCR, library preparation, and quality control assays.
• Support the preparation and submission of scientific manuscripts and grant proposals.
• Oversee junior laboratory personnel, providing mentorship and training.
• Assist with general lab management, including inventory control, ordering supplies, and maintaining laboratory compliance and safety standards.
• Perform additional duties as assigned.

Qualifications:

• Master of Science and 3 to 5 years of experience or equivalent combination of education and experience is required. A Ph.D. or equivalent in Neuroscience, Genetics, Bioinformatics, or a related discipline is preferred.
• Demonstrated expertise in single-cell/nuclei RNA sequencing and epigenetic techniques.
• Proficiency with short-read (Illumina) and long-read (ONT) sequencing technologies.
• Strong background in bioinformatics with proficiency in Linux-based HPC environments, scripting languages (R, Python), and bioinformatics software.
• Experience in animal handling, behavioral assays, molecular biology techniques, and general neuroscience methods.
• Excellent organizational skills, ability to manage multiple projects simultaneously, and strong interpersonal and communication skills.