from Technology Networks by Ruairi J Mackenzie
What is RNA-seq?
RNA-seq (RNA-sequencing) is a technique that can examine the quantity and sequences of RNA in a sample using next generation sequencing (NGS). It analyzes the transcriptome of gene expression patterns encoded within our RNA. Here, we look at why RNA-seq is useful, how the technique works, and the basic protocol which is commonly used today.
What are the applications of RNA-seq?
RNA-seq lets us investigate and discover the transcriptome, the total cellular content of RNAs including mRNA, rRNA and tRNA. Understanding the transcriptome is key if we are to connect the information on our genome with its functional protein expression. RNA-seq can tell us which genes are turned on in a cell, what their level of expression is, and at what times they are activated or shut off. This allows scientists to more deeply understand the biology of a cell and assess changes that may indicate disease. Some of the most popular techniques that use RNA-seq are transcriptional profiling, SNP identification, RNA editing and differential gene expression analysis.
(read more…)
from Technology Networks by Ruairi J Mackenzie
What is RNA-seq?
RNA-seq (RNA-sequencing) is a technique that can examine the quantity and sequences of RNA in a sample using next generation sequencing (NGS). It analyzes the transcriptome of gene expression patterns encoded within our RNA. Here, we look at why RNA-seq is useful, how the technique works, and the basic protocol which is commonly used today.
What are the applications of RNA-seq?
RNA-seq lets us investigate and discover the transcriptome, the total cellular content of RNAs including mRNA, rRNA and tRNA. Understanding the transcriptome is key if we are to connect the information on our genome with its functional protein expression. RNA-seq can tell us which genes are turned on in a cell, what their level of expression is, and at what times they are activated or shut off. This allows scientists to more deeply understand the biology of a cell and assess changes that may indicate disease. Some of the most popular techniques that use RNA-seq are transcriptional profiling, SNP identification, RNA editing and differential gene expression analysis.
(read more…)
Related Posts
RNA sequencing reveals functional chimeric mRNAs in mammalian immunity
Atlas of the brain’s striatum could guide researchers to new drug treatments
Immune cells offer insights on billion-dollar virus
A functionally integrated cross-tissue alternative splicing program during short-term calorie restriction
Dietary oxidized plant sterol shifts macrophage state to fuel aortic inflammation
Unlocking the past – new method helps gain insights into old tissue
Novel AI model trained on RNA-Seq data accurately detects key gene mutations and predicts biomarkers across 32 cancer types
Transcriptomic aging clock reveals age-related molecular patterns in opioid dependence
RNA sequencing helps predict stem cell transplant benefit in pediatric AML
Protein ‘switch’ determines whether liposarcoma cells will become aggressive
Precursor tRNAs sense temperature changes: heat stress-induced capped pre-tRNAs suppress protein synthesis
Ketamine increases neuroplasticity in female mice but not in males
Somatic mutations linked to vascular damage in progeria
Scientists map dormant cancer cells’ hideouts, opening new targets for treatment
Soluble signals released by neighboring cells direct how the human kidney is built
Genetics influence how cancer arises – and how it evolves
RNA-based testing uncovers extraordinary diversity in mutations driving lung cancer
Study offers new insights into why ex-smokers remain at elevated risk of lung disease
Learning the grammar of gene regulation
New findings could transform new treatment for rare brain tumor astroblastoma
from Technology Networks by Ruairi J Mackenzie
What is RNA-seq?
RNA-seq (RNA-sequencing) is a technique that can examine the quantity and sequences of RNA in a sample using next generation sequencing (NGS). It analyzes the transcriptome of gene expression patterns encoded within our RNA. Here, we look at why RNA-seq is useful, how the technique works, and the basic protocol which is commonly used today.
What are the applications of RNA-seq?
RNA-seq lets us investigate and discover the transcriptome, the total cellular content of RNAs including mRNA, rRNA and tRNA. Understanding the transcriptome is key if we are to connect the information on our genome with its functional protein expression. RNA-seq can tell us which genes are turned on in a cell, what their level of expression is, and at what times they are activated or shut off. This allows scientists to more deeply understand the biology of a cell and assess changes that may indicate disease. Some of the most popular techniques that use RNA-seq are transcriptional profiling, SNP identification, RNA editing and differential gene expression analysis.
(read more…)
Related Posts
RNA sequencing reveals functional chimeric mRNAs in mammalian immunity
Atlas of the brain’s striatum could guide researchers to new drug treatments
Immune cells offer insights on billion-dollar virus
A functionally integrated cross-tissue alternative splicing program during short-term calorie restriction
Dietary oxidized plant sterol shifts macrophage state to fuel aortic inflammation
Unlocking the past – new method helps gain insights into old tissue
Novel AI model trained on RNA-Seq data accurately detects key gene mutations and predicts biomarkers across 32 cancer types
Transcriptomic aging clock reveals age-related molecular patterns in opioid dependence
RNA sequencing helps predict stem cell transplant benefit in pediatric AML
Protein ‘switch’ determines whether liposarcoma cells will become aggressive
Precursor tRNAs sense temperature changes: heat stress-induced capped pre-tRNAs suppress protein synthesis
Ketamine increases neuroplasticity in female mice but not in males
Somatic mutations linked to vascular damage in progeria
Scientists map dormant cancer cells’ hideouts, opening new targets for treatment
Soluble signals released by neighboring cells direct how the human kidney is built
Genetics influence how cancer arises – and how it evolves
RNA-based testing uncovers extraordinary diversity in mutations driving lung cancer
Study offers new insights into why ex-smokers remain at elevated risk of lung disease
Learning the grammar of gene regulation
New findings could transform new treatment for rare brain tumor astroblastoma
Stay Connected
Submit a Post to the Blog
Recent Posts
Subscribe to the RNA-Seq Blog
RNA-Seq Products & Services