Single-cell RNA sequencing is fast becoming one the standard method for gene expression measurement, providing unique insights into cellular processes. A number of methods, based on general dimensionality reduction techniques, have been suggested to help infer and visualise the underlying ...
Read More »Single-cell RNA sequencing provides new insight into cellular composition of IDH1-mutant gliomas
Winner of the Preuss Research Award, Andrew Venteicher, MD, PhD, presented his research, Cellular Architecture of Human IDH1-mutant Gliomas Revealed Using Single-cell RNA Sequencing, during the 2016 American Association of Neurological Surgeons (AANS) Annual Scientific Meeting. Heterogeneity among tumor cells ...
Read More »SimSeq – A Nonparametric Approach to Simulation of RNA-Sequence Datasets
RNA sequencing analysis methods are often derived by relying on hypothetical parametric models for read counts that are not likely to be precisely satisfied in practice. Methods are often tested by analyzing data that have been simulated according to the ...
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