Boiler – Lossy compression of RNA-seq alignments using coverage vectors

June 1, 2016 Leave a comment 2,971 Views

Researchers from Johns Hopkins University have developed Boiler, a new software tool for compressing and querying large collections of RNA-seq alignments. Boiler discards most per-read data, keeping only a genomic coverage vector plus a few empirical distributions summarizing the alignments. Since ...

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