Motivated by the lack of easily implementable and generally applicable strategies to increase and assess data accuracy, researchers from the University of Georgia devised a novel label-free approach, termed REQUIEM, to address challenges in relative quantitation. For comparing the relative ...
Read More »EMSAR – estimation of transcript abundance from RNA-seq data by mappability-based segmentation and reclustering
RNA-seq has been widely used for genome-wide expression profiling. RNA-seq data typically consists of tens of millions of short sequenced reads from different transcripts. However, due to sequence similarity among genes and among isoforms, the source of a given read ...
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