Profiling the nucleobase and structure selectivity of anticancer drugs and other DNA alkylating agents by RNA-Seq

May 10, 2018 Leave a comment 1,357 Views

Drugs that covalently modify DNA are components of most chemotherapy regimens, often serving as first-line treatments. Classically the chemical reactivity of DNA alkylators has been determined in vitro with...

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Tag Archives: alkylating chemotherapeutics

Profiling the nucleobase and structure selectivity of anticancer drugs and other DNA alkylating agents by RNA-Seq

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