Profiling the nucleobase and structure selectivity of anticancer drugs and other DNA alkylating agents by RNA-Seq

May 10, 2018 Leave a comment 1,766 Views

Drugs that covalently modify DNA are components of most chemotherapy regimens, often serving as first-line treatments. Classically the chemical reactivity of DNA alkylators has been determined in vitro with...

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Tag Archives: alkylating chemotherapeutics

Profiling the nucleobase and structure selectivity of anticancer drugs and other DNA alkylating agents by RNA-Seq

scONE-seq – A single-cell multi-omics method enables simultaneous dissection of phenotype and genotype heterogeneity from frozen tumors

Phasik – inferring cell cycle phases from a partially temporal network of protein interactions

Single-cell transcriptomic profiling of Crohn’s disease reveals a detailed picture of inflammation in the gut

Gene expression model inference from snapshot RNA data using Bayesian non-parametrics

LeukemiaDB – a comprehensive human leukemia transcriptome database

Temporal transcriptomics analysis finds mating causes ‘jet lag’ in female fruit flies, changing behavior

DGAN – improved downstream functional analysis of single-cell RNA-sequence data