Analysis of allelic expression patterns in clonal somatic cells by single-cell RNA-seq

October 19, 2016 Leave a comment 2,920 Views

Cellular heterogeneity can emerge from the expression of only one parental allele. However, it has remained controversial whether, or to what degree, random monoallelic expression of autosomal genes (aRME) is mitotically inherited (clonal) or stochastic (dynamic) in somatic cells, particularly ...

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