Recommendations for Accurate Resolution of Gene and Isoform Allele-Specific Expression in RNA-Seq Data

May 18, 2015 Leave a comment 6,962 Views

Genetic variation modulates gene expression transcriptionally or post-transcriptionally, and can profoundly alter an individual’s phenotype. Measuring allelic differential expression at heterozygous loci within an individual, a phenomenon called allele-specific expression (ASE), can assist in identifying such factors. Massively parallel DNA ...

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Recommendations for Accurate Resolution of Gene and Isoform Allele-Specific Expression in RNA-Seq Data

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