Direct testing for allele-specific expression differences between conditions

November 27, 2017 Leave a comment 6,009 Views

Allelic imbalance (AI) indicates the presence of functional variation in cis regulatory regions. Detecting cis regulatory differences using AI is widespread, yet there is no formal statistical methodology that tests whether AI differs between conditions. Here a team led by ...

A Novel Statistical Approach for Jointly Analyzing RNA-seq Data from Reciprocal Crosses and Inbred Lines

February 28, 2014 Leave a comment 6,018 Views

RNA sequencing (RNA-seq) not only measures total gene expression but may also measure allele-specific gene expression in diploid individuals. RNA-seq data collected from F1 reciprocal crosses in mouse can powerfully dissect strain and parent-of-origin effects on allelic imbalance of gene ...

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Tag Archives: Allelic imbalance

Direct testing for allele-specific expression differences between conditions

A Novel Statistical Approach for Jointly Analyzing RNA-seq Data from Reciprocal Crosses and Inbred Lines

Researchers construct a high-resolution single-nucleus RNA sequencing (snRNA-seq) analysis of gene expression changes across all brain cell

Zebrahub – a single-embryo single-cell RNA sequencing atlas of zebrafish development

Post-doc position available – RNA Accelerator Inflammation and Immunology

BEETLE ATLAS – a definitive, tissue-specific transcriptomic resource based on RNA-Seq data for the Tribolium community

ElasticBLAST – accelerating sequence search via cloud computing

TileDB launches cross-language access to single-cell data

Researchers have developed an instrument-free single-cell RNA sequencing using a reversible hydrogel for cell-specific barcoding