RNA-Seq Blog Transcriptome Research & Industry News
A team of scientists has utilized new technologies for mapping gene expression that provide a fuller picture of the mechanisms that contribute to...
Read More »Spatial transcriptomics creates multidimensional ALS gene expression atlas
New RNA Sequencing method for studying ALS more effectively
The neurodegenerative disease ALS causes motor neuron death and paralysis. However, long before the cells die, they lose contact with the muscles as their axons atrophy. Researchers at Karolinska...
Read More »RNA-Seq sheds light on motor neuron death in ALS
A new study from Crick researchers shows that collaboration can be easy when you are part of a culture that supports it. We caught up with the scientists involved to find out how working...
Read More »A new RNA-Seq based test for ALS
A simple blood test may help diagnose and develop therapies for the most common genetic form of ALS. The strategy, proposed by a research team led by the University of Florida’s Maurice Swanson in...
Read More »RNA-Seq reveals a novel therapeutic strategy for ALS treatment
Amyotrophic lateral sclerosis (ALS) is a fatal heterogeneous neurodegenerative disease that lacks effective treatment option. Researchers at Genervon Biopharmaceuticals hypothesized that the traditional single-target approach to treat neurodegenerative...
Read More »A new resource may help RNA researchers go long in ALS
The ALS Research Forum – A new genomic resource may help researchers unravel the role of key RNA-binding proteins in ALS. The atlas, developed at the Riken Institute in Yokohama, Japan, contains 27,919 long non-coding RNAs – including 19,175 potentially ...
Read More »Revolutionary method to map brains at single-neuron resolution successfully demonstrated
MAPseq uses RNA sequencing to rapidly and inexpensively find the diverse destinations of thousands of neurons in a single experiment in a single animal Neuroscientists have published in Neuron the details of a revolutionary new way of mapping the brain ...
Read More »Phenotype prediction from alternative splicing and gene expression data
A central task of bioinformatics is to develop sensitive and specific means of providing medical prognoses from biomarker patterns. Common methods to predict phenotypes in RNA-Seq datasets utilize machine learning algorithms trained via gene expression. Isoforms, however, generated from alternative ...
Read More »ALS Ice Bucket Challenge Funds RNA-Seq Experiments
from Gizmodo by Jennifer Ouellette Last year’s hugely popular “ice bucket challenge” saw celebrities pouring buckets of ice water over their heads to help fight Lou Gehrig’s Disease (ALS). Skeptics dismissed it as mere “slacktivism,” but researchers told us that ...
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