Researchers at the University of California San Diego discovered that high blood levels of RNA produced by the PHGDH gene could serve as a biomarker...
Read More »A new RNA-Seq based test for ALS
A simple blood test may help diagnose and develop therapies for the most common genetic form of ALS. The strategy, proposed by a research team led by the University of Florida’s Maurice Swanson in...
Read More »A new generation of single-cell sequencing methods enables a more detailed brain map
Researchers have developed new single-cell sequencing methods that could be used to map the cell origins of various brain disorders, including Alzheimer’s, Parkinson’s, schizophrenia and bipolar disorder. By analyzing individual nuclei of cells from adult human brains, researchers at the ...
Read More »RNA-Seq reveals mRNA stability a marker in Alzheimer’s patients
Through mathematical modeling and collaboration with scientists at the University of California San Francisco (UCSF), McGill researchers, including Rached Alkallas, graduate student in the Department of Human Genetics and the primary author of the seminal study published in Nature Communications, ...
Read More »Studying Alzheimer’s at single cell resolution
from News- Medical.net Cells vary considerably within cell populations, including within a particular type of tissue or cell. No two cells have the same response to their surroundings, since each cell’s behavior is dictated by the particular genes it expresses ...
Read More »Researchers combine CRISPR gene editing and single cell genomic profiling
A new combined method may finally give scientists a tool fine enough to probe life’s most nuanced processes What combinations of mutations help cancer cells survive? Which cells in the brain are involved in the onset of Alzheimer’s? How do ...
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