Genome-wide profiling of the 3′ ends of polyadenylated RNAs

June 14, 2017 Leave a comment 6,269 Views

Alternative polyadenylation (APA) diversifies the 3′ termini of a majority of mRNAs in most eukaryotes, and is consequently inferred to have substantial consequences for the utilization of post-transcriptional regulatory mechanisms. Since conventional RNA-sequencing methods do not accurately define mRNA termini, ...

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Genome-wide profiling of the 3′ ends of polyadenylated RNAs

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