dupRadar – a Bioconductor package for the assessment of PCR artifacts in RNA-Seq data

April 15, 2016 Leave a comment 6,839 Views

PCR clonal artefacts originating from NGS library preparation can affect both genomic as well as RNA-Seq applications when protocols are pushed to their limits. In RNA-Seq however the artifactual reads are not easy to tell apart from normal read duplication ...

RDDpred – a condition-specific RNA-editing prediction model from RNA-seq data

February 3, 2016 Leave a comment 3,563 Views

RNA-editing is an important post-transcriptional RNA sequence modification performed by two catalytic enzymes, “ADAR”(A-to-I) and “APOBEC”(C-to-U). By utilizing high-throughput sequencing technologies, the biological function of RNA-editing has been actively investigated. Currently, RNA-editing is considered to be a key regulator that ...

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Tag Archives: artefacts

dupRadar – a Bioconductor package for the assessment of PCR artifacts in RNA-Seq data

RDDpred – a condition-specific RNA-editing prediction model from RNA-seq data

Novel guidelines help select optimal deconvolution method

An RNA-Seq framework for profiling target selectivity and physiological effects of antisense peptide nucleic acids (PNAs)

Single cell sequencing unravels molecular identity of rare renal cell types

SMIXnorm – fast and accurate RNA-Seq data normalization for FFPE Samples

TEA-seq – simultaneous trimodal single-cell measurement of transcripts, epitopes, and chromatin accessibility

First use of both bulk and single-cell RNA sequencing of human bladder tumors to study resistance to immunotherapy

Post-doc position available – transcriptome bioinformatics and RNA sequencing