dupRadar – a Bioconductor package for the assessment of PCR artifacts in RNA-Seq data

April 15, 2016 Leave a comment 7,413 Views

PCR clonal artefacts originating from NGS library preparation can affect both genomic as well as RNA-Seq applications when protocols are pushed to their limits. In RNA-Seq however the artifactual reads are not easy to tell apart from normal read duplication ...

RDDpred – a condition-specific RNA-editing prediction model from RNA-seq data

February 3, 2016 Leave a comment 3,723 Views

RNA-editing is an important post-transcriptional RNA sequence modification performed by two catalytic enzymes, “ADAR”(A-to-I) and “APOBEC”(C-to-U). By utilizing high-throughput sequencing technologies, the biological function of RNA-editing has been actively investigated. Currently, RNA-editing is considered to be a key regulator that ...

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Tag Archives: artefacts

dupRadar – a Bioconductor package for the assessment of PCR artifacts in RNA-Seq data

RDDpred – a condition-specific RNA-editing prediction model from RNA-seq data

RNA-Scoop – interactive visualization of transcripts in single-cell transcriptomes

SCHNAPPs – Single Cell sHiNy APPlication(s)

CircAID-p-seq – a PCR-free library preparation for selective 3′ phospho-RNA sequencing

Nanopore ReCappable Sequencing (NRCeq) – a new technique that can identify capped full-length RNAs

CLEARER – a machine learning approach for predicting essential genes across eukaryotes

scRNA-Seq reveals how genetic ancestry shapes immune response to influenza virus

Single-cell RNA sequencing and bioinformatics as tools to decipher cancer heterogenicity and mechanisms of drug resistance